Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Severe anemia is a major cause of death by malaria. The loss of uninfected erythrocytes is
an important contributor to malarial anemia; however, the mechanisms underlying this …

Genetics alone cannot explain most cases of rheumatoid arthritis (RA). Thus, investigating
environmental factors such as the gut microbiota may provide new insights into the initiation …

Plasmodium vivax causes approximately 100 million clinical malaria cases yearly,. The
basis of protective immunity is poorly understood and thought to be mediated by antibodies …

Anemia is a common complication of malaria that is characterized by the loss of infected and
uninfected erythrocytes. In mouse malaria models, clearance of uninfected erythrocytes is …

Increased susceptibility to co-infection with enteric Gram-negative bacteria, particularly non-
typhoidal Salmonella, is reported in malaria and Oroya fever (Bartonella bacilliformis …

In Plasmodium falciparum malaria, CD8+ T cells play a double-edged role. Liver-stage
specific CD8+ T cells can confer protection, as has been shown in several vaccine studies …

Background Malaria-associated anaemia, arising from symptomatic, asymptomatic and
submicroscopic infections, is a significant cause of morbidity worldwide. Induced blood …

Background Plasmodium vivax is the causative agent of human malaria of large geographic
distribution, with 35 million cases annually. In Brazil, it is the most prevalent species, being …

Plasmodium parasites cause malaria with disease outcomes ranging from mild illness to
deadly complications such as severe malarial anemia (SMA), pulmonary edema, acute renal …