Towards advances in medicinal plant antimicrobial activity: A review study on challenges and future perspectives

N Vaou, E Stavropoulou, C Voidarou, C Tsigalou… - Microorganisms, 2021 - mdpi.com
The increasing incidence of drug-resistant pathogens raises an urgent need to identify and
isolate new bioactive compounds from medicinal plants using standardized modern …

Synergy and antagonism in natural product extracts: when 1+ 1 does not equal 2

LK Caesar, NB Cech - Natural product reports, 2019 - pubs.rsc.org
Covering: 2000 to 2019 According to a 2012 survey from the Centers for Disease Control
and Prevention, approximately 18% of the US population uses natural products (including …

Interactions between medical plant-derived bioactive compounds: focus on antimicrobial combination effects

N Vaou, E Stavropoulou, C Voidarou, Z Tsakris… - Antibiotics, 2022 - mdpi.com
It is accepted that the medicinal use of complex mixtures of plant-derived bioactive
compounds is more effective than purified bioactive compounds due to beneficial …

Interactions between antidiabetic drugs and herbs: an overview of mechanisms of action and clinical implications

RC Gupta, D Chang, S Nammi, A Bensoussan… - Diabetology & metabolic …, 2017 - Springer
Diabetes is a complex condition with a variety of causes and pathophysiologies. The current
single target approach has not provided ideal clinical outcomes for the treatment of the …

Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy

T Efferth, E Koch - Current drug targets, 2011 - ingentaconnect.com
Drugs derived from natural resources represent a significant segment of the pharmaceutical
market as compared to randomly synthesized compounds. It is a goal of drug development …

Plant-based antimicrobial studies–methods and approaches to study the interaction between natural products

S van Vuuren, A Viljoen - Planta medica, 2011 - thieme-connect.com
The therapeutic value of synergistic interactions has been known since antiquity, and many
different cultural healing systems still rely on this principle in the belief that combination …

The methodological trends of traditional herbal medicine employing network pharmacology

WY Lee, CY Lee, YS Kim, CE Kim - Biomolecules, 2019 - mdpi.com
Natural products, including traditional herbal medicine (THM), are known to exert their
therapeutic effects by acting on multiple targets, so researchers have employed network …

Assessment of herbal medicinal products: challenges, and opportunities to increase the knowledge base for safety assessment

SA Jordan, DG Cunningham, RJ Marles - Toxicology and applied …, 2010 - Elsevier
Although herbal medicinal products (HMP) have been perceived by the public as relatively
low risk, there has been more recognition of the potential risks associated with this type of …

An overview of the evidence and mechanisms of herb–drug interactions

PS Fasinu, PJ Bouic, B Rosenkranz - Frontiers in pharmacology, 2012 - frontiersin.org
Despite the lack of sufficient information on the safety of herbal products, their use as
alternative and/or complementary medicine is globally popular. There is also an increasing …

A call for using natural compounds in the development of new antimalarial treatments–an introduction

H Ginsburg, E Deharo - Malaria journal, 2011 - Springer
Natural compounds, mostly from plants, have been the mainstay of traditional medicine for
thousands of years. They have also been the source of lead compounds for modern …