eIF3: a versatile scaffold for translation initiation complexes
AG Hinnebusch - Trends in biochemical sciences, 2006 - cell.com
Translation initiation in eukaryotes depends on many eukaryotic initiation factors (eIFs) that
stimulate both recruitment of the initiator tRNA, Met-tRNA i Met, and mRNA to the 40S …
stimulate both recruitment of the initiator tRNA, Met-tRNA i Met, and mRNA to the 40S …
Translation initiation: structures, mechanisms and evolution
A Marintchev, G Wagner - Quarterly reviews of biophysics, 2004 - cambridge.org
Translation, the process of mRNA-encoded protein synthesis, requires a complex apparatus,
composed of the ribosome, tRNAs and additional protein factors, including aminoacyl tRNA …
composed of the ribosome, tRNAs and additional protein factors, including aminoacyl tRNA …
The essential Gcd10p–Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA
J Anderson, L Phan, R Cuesta, BA Carlson… - Genes & …, 1998 - genesdev.cshlp.org
Gcd10p and Gcd14p are essential proteins required for the initiation of protein synthesis and
translational repression of GCN4 mRNA. The phenotypes of gcd10 mutants were …
translational repression of GCN4 mRNA. The phenotypes of gcd10 mutants were …
unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA
SL Hunt, JJ Hsuan, N Totty… - Genes & …, 1999 - genesdev.cshlp.org
Initiation of translation of the animal picornavirus RNAs occurs via a mechanism of direct
ribosome entry, which requires a segment of the 5′ UTR of the RNA, known as the internal …
ribosome entry, which requires a segment of the 5′ UTR of the RNA, known as the internal …
Reconstitution reveals the functional core of mammalian eIF3
M Masutani, N Sonenberg, S Yokoyama… - The EMBO …, 2007 - embopress.org
Eukaryotic translation initiation factor (eIF) 3 is the largest eIF (∼ 650 kDa), consisting of 10–
13 different polypeptide subunits in mammalian cells. To understand the role of each …
13 different polypeptide subunits in mammalian cells. To understand the role of each …
Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5
L Phan, X Zhang, K Asano, J Anderson… - … and cellular biology, 1998 - Am Soc Microbiol
Only five of the nine subunits of human eukaryotic translation initiation factor 3 (eIF3) have
recognizable homologs encoded in the Saccharomyces cerevisiae genome, and only two of …
recognizable homologs encoded in the Saccharomyces cerevisiae genome, and only two of …
Involvement of Arabidopsis RACK1 in protein translation and its regulation by abscisic acid
Earlier studies have shown that RACK1 functions as a negative regulator of abscisic acid
(ABA) responses in Arabidopsis (Arabidopsis thaliana), but the molecular mechanism of the …
(ABA) responses in Arabidopsis (Arabidopsis thaliana), but the molecular mechanism of the …
Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits: possible roles in RNA binding and macromolecular assembly
K Asano, HP Vornlocher, NJ Richter-Cook… - Journal of Biological …, 1997 - ASBMB
The mammalian translation initiation factor 3 (eIF3), is a multiprotein complex of∼ 600 kDa
that binds to the 40 S ribosome and promotes the binding of methionyl-tRNA i and mRNA …
that binds to the 40 S ribosome and promotes the binding of methionyl-tRNA i and mRNA …
The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal …
T Achsel, K Ahrens, H Brahms… - … and cellular biology, 1998 - Am Soc Microbiol
The human small nuclear ribonucleoprotein (snRNP) U5 is biochemically the most complex
of the snRNP particles, containing not only the Sm core proteins but also 10 particle-specific …
of the snRNP particles, containing not only the Sm core proteins but also 10 particle-specific …
Complex formation by all five homologues of mammalian translation initiation factor 3 subunits from yeast Saccharomyces cerevisiae
K Asano, L Phan, J Anderson… - Journal of Biological …, 1998 - ASBMB
The PRT1, TIF34, GCD10, and SUI1 proteins ofSaccharomyces cerevisiae were found
previously to copurify with eukaryotic translation initiation factor 3 (eIF3) activity. Although …
previously to copurify with eukaryotic translation initiation factor 3 (eIF3) activity. Although …