The role of microRNAs, long non-coding RNAs, and circular RNAs in cervical cancer

ML Tornesello, R Faraonio, L Buonaguro… - Frontiers in …, 2020 - frontiersin.org
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and
constitutive expression of viral oncogenes have been recognized as the main cause of the …

microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer

JS Nahand, S Taghizadeh‐boroujeni… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer
could be observed in women who infected with papillomavirus, regular oral contraceptives …

[HTML][HTML] DUBs, hypoxia, and cancer

D Mennerich, K Kubaichuk, T Kietzmann - Trends in cancer, 2019 - cell.com
Alterations in protein ubiquitylation and hypoxia are commonly associated with cancer.
Ubiquitylation is carried out by three sequentially acting ubiquitylating enzymes and can be …

EMT in cervical cancer: its role in tumour progression and response to therapy

R Qureshi, H Arora, MA Rizvi - Cancer letters, 2015 - Elsevier
The prognosis of cervical patients significantly decreases as the cancer metastasizes to
other parts of the body. The epithelial to mesenchymal transition (EMT) plays an important …

Epigenetics and cervical cancer: from pathogenesis to therapy

J Fang, H Zhang, S Jin - Tumor Biology, 2014 - Springer
Although human papillomavirus (HPV) infection has been found in most of the cervical
cancer cases, additional genetic and epigenetic changes are required for disease …

miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1

Y Liu, R Liu, F Yang, R Cheng, X Chen, S Cui, Y Gu… - Molecular cancer, 2017 - Springer
Background Colorectal cancer (CRC) is a major worldwide health problem due to its high
prevalence and mortality rate. T-cell intracellular antigen 1 (TIA1) is an important tumor …

IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs

JM Wang, Y Qiu, Z Yang, H Kim, Q Qian, Q Sun… - Science …, 2018 - science.org
Obesity or a high-fat diet represses the endoribonuclease activity of inositol-requiring
enzyme 1α (IRE1α), a transducer of the unfolded protein response (UPR) in cells under …

Increased exosomal microRNA-21 and microRNA-146a levels in the cervicovaginal lavage specimens of patients with cervical cancer

J Liu, H Sun, X Wang, Q Yu, S Li, X Yu… - International journal of …, 2014 - mdpi.com
Well-run screening programs for cervical cancer in the population at risk have been shown
to result in a sharp decrease in the incidence and mortality of cervical cancer in a number of …

Identification of a six‐miRNA panel in serum benefiting pancreatic cancer diagnosis

X Zou, J Wei, Z Huang, X Zhou, Z Lu, W Zhu… - Cancer …, 2019 - Wiley Online Library
Pancreatic cancer (PC) has posed a great health threat to a growing number of people all
over the world. Detection of serum miRNAs, being sensitive, noninvasive, and easy to …

MicroRNA in cervical cancer: OncomiRs and tumor suppressor miRs in diagnosis and treatment

K Banno, M Iida, M Yanokura, I Kisu… - The Scientific World …, 2014 - Wiley Online Library
Cervical cancer is a female‐specific disease with a high incidence and mortality. MicroRNAs
(miRNAs) are implicated in posttranscriptional regulation of gene expression and in the …