Structure-function and application of plant lectins in disease biology and immunity

A Mishra, A Behura, S Mawatwal, A Kumar… - Food and Chemical …, 2019 - Elsevier
Lectins are proteins with a high degree of stereospecificity to recognize various sugar
structures and form reversible linkages upon interaction with glyco-conjugate complexes …

Targeting the immune system with plant lectins to combat microbial infections

JJB Jandú, RN Moraes Neto, A Zagmignan… - Frontiers in …, 2017 - frontiersin.org
The arsenal of drugs available to treat infections caused by eukaryotic and prokaryotic
microbes has been declining exponentially due to antimicrobial resistance phenomenon …

Candida infections and human defensins

V Polesello, L Segat, S Crovella… - Protein and peptide …, 2017 - ingentaconnect.com
Background: Candida species infections are an important worldwide health issue since they
do not only affect immunocompromised patients but also healthy individuals. The host …

Eutirucallin, a RIP-2 Type Lectin from the Latex of Euphorbia tirucalli L. Presents Proinflammatory Properties

SS Santana, ML Gennari-Cardoso, FC Carvalho… - PLoS one, 2014 - journals.plos.org
Lectins are carbohydrate-binding proteins that recognize and modulate physiological
activities and have been used as a toll for detection and identification of biomolecules, and …

Antifungal potential of eugenyl acetate against clinical isolates of Candida species

KS Musthafa, J Hmoteh, B Thamjarungwong… - Microbial …, 2016 - Elsevier
The study evaluated the efficiency of eugenyl acetate (EA), a phytochemical in clove
essential oil, against clinical isolates of Candida albicans, Candida parapsilosis, Candida …

Treatment with pCramoll Alone and in Combination with Fluconazole Provides Therapeutic Benefits in C. gattii Infected Mice

JJ Jandú, MC Costa, JRA Santos… - Frontiers in cellular …, 2017 - frontiersin.org
Cryptococcus gattii is one of the main causative agents of cryptococcosis in
immunocompetent individuals. Treatment of the infection is based on the use of …

Neutrophils Contribute to the Protection Conferred by ArtinM against Intracellular Pathogens: A Study on Leishmania major

R Ricci-Azevedo, AF Oliveira… - PLoS neglected …, 2016 - journals.plos.org
ArtinM, a D-mannose binding lectin from Artocarpus heterophyllus, has immunomodulatory
activities through its interaction with N-glycans of immune cells, culminating with the …

Adjuvant ArtinM favored the host immunity against Cryptococcus gattii infection in C57BL/6 mice

PK Martins Oliveira-Brito, GY de Campos… - …, 2024 - Taylor & Francis
Aim: Cryptococcus gattii causes a severe fungal infection with high mortality rate among
immunosuppressed and immunocompetent individuals. Due to limitation of current …

The role of annexin A1 in Candida albicans and Candida auris infections in murine neutrophils

JM Sanches, L Rossato, I Lice… - Microbial …, 2021 - Elsevier
Abstract Annexin A1 (AnxA1) is an anti-inflammatory protein expressed in various cell types,
especially macrophages and neutrophils. Because neutrophils play important roles in …

Effect of ArtinM on Human Blood Cells During Infection With Paracoccidioides brasiliensis

LP Ruas, LM Genaro, AS Justo-Junior… - Frontiers in …, 2018 - frontiersin.org
Infections caused by fungi are prominent in our environment and can be potentially fatal.
paracoccidioidomycosis (PCM), caused by fungi of the Paracoccidioides genus, is the most …