Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile elements, make up a significant portion of the genomes of higher animals. TEs contribute in …
M Neou, C Villa, R Armignacco, A Jouinot… - Cancer cell, 2020 - cell.com
Pituitary neuroendocrine tumors (PitNETs) are common, with five main histological subtypes: lactotroph, somatotroph, and thyrotroph (POU1F1/PIT1 lineage); corticotroph (TBX19/TPIT …
Cys2-His2 zinc finger genes (ZNFs) form the largest family of transcription factors in metazoans. ZNF evolution is highly dynamic and characterized by the rapid expansion and …
PE Bonté, YA Arribas, A Merlotti, M Carrascal… - Cell Reports, 2022 - cell.com
We analyze transposable elements (TEs) in glioblastoma (GBM) patients using a proteogenomic pipeline that combines single-cell transcriptomics, bulk RNA sequencing …
JZ Shen, Z Qiu, Q Wu, D Finlay, G Garcia, D Sun… - Cell, 2021 - cell.com
Repetitive elements (REs) compose∼ 50% of the human genome and are normally transcriptionally silenced, although the mechanism has remained elusive. Through an RNAi …
Most living organisms have in their genome a sizable proportion of DNA sequences capable of mobilization; these sequences are commonly referred to as transposons, transposable …
The etiology of the majority of human cancers is associated with a myriad of environmental causes, including physical, chemical, and biological factors. DNA damage induced by such …
W Weng, H Li, A Goel - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2019 - Elsevier
Piwi-interacting RNAs (piRNAs) are a very recently discovered class of small non-coding RNAs (ncRNAs), with approximately 20,000 piRNA genes already identified within the …
YV Teo, M Capri, C Morsiani, G Pizza, AMC Faria… - Aging cell, 2019 - Wiley Online Library
Cell‐free DNA (cfDNA) is present in the circulating plasma and other body fluids and is known to originate mainly from apoptotic cells. Here, we provide the first in vivo evidence of …