The prognostic significance of perineural invasion in prostatic cancer biopsies: a systematic review

P Harnden, MD Shelley, H Clements, B Coles… - Cancer, 2007 - Wiley Online Library
Men with clinically localized prostate cancer are faced with a wide range of treatment
options, and only Gleason grading is universally used as a histopathological prognostic …

Perineural invasion as an independent predictor of biochemical recurrence in prostate cancer following radical prostatectomy or radiotherapy: a systematic review and …

L Zhang, B Wu, Z Zha, W Qu, H Zhao, J Yuan, Y Feng - BMC urology, 2018 - Springer
Background Although numerous studies have shown that perineural invasion (PNI) is linked
to prostate cancer (PCa) risk, the results have been inconsistent. This study aimed to explore …

Dose-based radiomic analysis (dosiomics) for intensity modulated radiation therapy in patients with prostate cancer: correlation between planned dose distribution …

Y Murakami, T Soyano, T Kozuka, M Ushijima… - International Journal of …, 2022 - Elsevier
Purpose Although radiation therapy is one of the most significant treatment modalities for
localized prostate cancer, the prognostic factors for biochemical recurrence (BCR) regarding …

Analysis of biochemical control and prognostic factors in patients treated with either low-dose three-dimensional conformal radiation therapy or high-dose intensity …

SA Vora, WW Wong, SE Schild, GA Ezzell… - International Journal of …, 2007 - Elsevier
Purpose: To identify prognostic factors and evaluate biochemical control rates for patients
with localized prostate cancer treated with either high-dose intensity-modulated …

Interobserver and intraobserver reproducibility in digital and routine microscopic assessment of prostate needle biopsies

PA Rodriguez-Urrego, AM Cronin, HA Al-Ahmadie… - Human pathology, 2011 - Elsevier
Advances in whole slide digital imaging in the past decade necessitate validation of these
tools in each organ system in advance of clinical adoption. We assessed reproducibility in …

Perineural invasion is a marker for pathologically advanced disease in localized prostate cancer

IH Lee, R Roberts, RB Shah, KJ Wojno, JT Wei… - International Journal of …, 2007 - Elsevier
Purpose: To determine if perineural invasion (PNI) should be included in addition to prostate-
specific antigen (PSA), biopsy Gleason score, and clinical T-stage for risk-stratification of …

Perineural invasion predicts increased recurrence, metastasis, and death from prostate cancer following treatment with dose-escalated radiation therapy

FY Feng, Y Qian, MH Stenmark, S Halverson… - International Journal of …, 2011 - Elsevier
PURPOSE: To assess the prognostic value of perineural invasion (PNI) for patients treated
with dose-escalated external-beam radiation therapy for prostate cancer. METHODS AND …

Perineural invasion affects biochemical recurrence-free survival in patients with prostate cancer treated with definitive external beam radiotherapy

MY Hsiang-Hsuan, DY Song, YY Tsai, T Thompson… - Urology, 2007 - Elsevier
OBJECTIVES: To assess the prognostic effect of perineural invasion (PNI) for patients
undergoing external beam radiotherapy for prostate cancer. METHODS: We evaluated 657 …

Australian & New Zealand Faculty of Radiation Oncology Genito‐Urinary Group: 2010 consensus guidelines for definitive external beam radiotherapy for prostate …

AJ Hayden, JM Martin, AB Kneebone… - Journal of Medical …, 2010 - Wiley Online Library
External beam radiotherapy for prostate cancer has undergone substantial technological
and clinical advances in the recent years. The Australian & New Zealand Faculty of …

Perineural invasion associated with increased cancer-specific mortality after external beam radiation therapy for men with low-and intermediate-risk prostate cancer

C Beard, D Schultz, M Loffredo, K Cote… - International Journal of …, 2006 - Elsevier
Purpose: To identify an association between perineural invasion (PNI) and cancer-specific
survival in patients with prostate cancer after standard-dose external beam radiation therapy …