Bilirubin-Induced Neurologic Damage — Mechanisms and Management Approaches | New
England Journal of Medicine Skip to main content The New England Journal of Medicine …

A breakthrough discovery 60 years ago by Cremer et al. has since changed the way we treat
infants with hyperbilirubinemia and saved the lives of millions from death and disabilities.“ …

Jaundice is the most common reason for instituting treatment in otherwise healthy as well as
sick newborn infants. Herein, we describe the process employed in Norway to forge …

Osteosarcoma (OS) is the most common primary malignant bone tumor that mainly affects
the pediatric and adolescent population; limb salvage treatment has become one of the most …

Photoimaging and phototherapy have become major platforms for the diagnosis and
treatment of various health complications. These applications require a photosensitizer (PS) …

Early clinical jaundice or rapidly developing hyperbilirubinemia is often a sign of hemolysis,
the differential diagnosis of which commonly includes immune-mediated disorders, red cell …

Background The clinical part of this randomized controlled trial concerning phototherapy of
neonates with hyperbilirubinemia showed that the recommended blue–green LED light (≈ …

BACKGROUND AND OBJECTIVE: Using light-emitting diodes during conventional
phototherapy, it is possible to reduce the distance from light source to infant, thus increasing …

When exposed to light, bilirubin undergoes photoisomerization which are water-soluble and
can be excreted in bile and urine. Photoisomerization starts as soon as the lights turned on …

The effectiveness of phototherapy for neonatal hyperbilirubinemia based on Danish clinical
trials is presented. Randomized controlled trials on the quality of light showed that blue …