Monoclonal antibodies constitute a promising class of targeted anticancer agents that
enhance natural immune system functions to suppress cancer cell activity and eliminate …

Adoptive cell therapy (ACT) has seen a steep rise of new therapeutic approaches in its
immune-oncology pipeline over the last years. This is in great part due to the recent …

Monoclonal antibodies (mAbs) are valuable as research reagents, in diagnosis and in
therapy. Their high specificity, the ease in production, favorable biophysical properties and …

Acute Respiratory Distress Syndrome (ARDS) is an illness that typically develops in people
who are significantly ill or have serious injuries. ARDS is characterized by fluid build-up that …

Background The recent COVID vaccinations have successfully reduced death and severity
but did not stop the transmission of viruses by the emerging SARS-CoV-2 strain. There is a …

The immune system is tasked to keep our body unharmed and healthy. In the immune
system, B-and T-lymphocytes are the two main components working together to stop and …

Advances in reading, writing, and editing DNA are providing unprecedented insights into the
complexity of immunological systems. This combination of systems and synthetic biology …

The T-cell receptor (TCR) is a crucial molecule in cellular immunity. The single-chain T-cell
receptor (scTCR) is a potential format in TCR therapeutics because it eliminates the …

Soluble T‐cell receptors (TCRs) have recently gained visibility as target‐recognition units of
anticancer immunotherapeutic agents. Here, we improved the thermal stability of the well …

Abstract γδ T cells, especially Vγ9Vδ2 T cells, play an important role in mycobacterial
infection. We have identified some Vγ9Vδ2 T cells that recognize protein/peptide antigens …