Current challenges and best-practice protocols for microbiome analysis
Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …
sequencing techniques has significantly enhanced our understanding on metabolic …
The calpain system
DE Goll, VF Thompson, H Li, WEI Wei… - Physiological …, 2003 - journals.physiology.org
Abstract Goll, Darrel E., Valery F. Thompson, Hongqi Li, Wei Wei, and Jinyang Cong. The
Calpain System. Physiol Rev 83: 731–801, 2003; 10.1152/physrev. 00029.2002.—The …
Calpain System. Physiol Rev 83: 731–801, 2003; 10.1152/physrev. 00029.2002.—The …
Genomic insights into the Ixodes scapularis tick vector of Lyme disease
Ticks transmit more pathogens to humans and animals than any other arthropod. We
describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors …
describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors …
[HTML][HTML] A large-scale evaluation of computational protein function prediction
Automated annotation of protein function is challenging. As the number of sequenced
genomes rapidly grows, the overwhelming majority of protein products can only be …
genomes rapidly grows, the overwhelming majority of protein products can only be …
Genomics and evolution of protein phosphatases
Protein phosphatases are the essential opposite to protein kinases; together, these enzymes
regulate all protein phosphorylation and most cellular processes. To better understand the …
regulate all protein phosphorylation and most cellular processes. To better understand the …
Initial sequencing and analysis of the human genome
US DOE Joint Genome Institute: Hawkins Trevor 4 … - Nature, 2001 - nature.com
The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …
physiology, medicine and evolution. Here we report the results of an international …
MUSCLE: multiple sequence alignment with high accuracy and high throughput
RC Edgar - Nucleic acids research, 2004 - academic.oup.com
We describe MUSCLE, a new computer program for creating multiple alignments of protein
sequences. Elements of the algorithm include fast distance estimation using k mer counting …
sequences. Elements of the algorithm include fast distance estimation using k mer counting …
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
RC Edgar - BMC bioinformatics, 2004 - Springer
Background In a previous paper, we introduced MUSCLE, a new program for creating
multiple alignments of protein sequences, giving a brief summary of the algorithm and …
multiple alignments of protein sequences, giving a brief summary of the algorithm and …
MuSiC: identifying mutational significance in cancer genomes
Massively parallel sequencing technology and the associated rapidly decreasing
sequencing costs have enabled systemic analyses of somatic mutations in large cohorts of …
sequencing costs have enabled systemic analyses of somatic mutations in large cohorts of …
InterProScan–an integration platform for the signature-recognition methods in InterPro
EM Zdobnov, R Apweiler - Bioinformatics, 2001 - academic.oup.com
InterProScan is a tool that scans given protein sequences against the protein signatures of
the InterPro member databases, currently–PROSITE, PRINTS, Pfam, ProDom and SMART …
the InterPro member databases, currently–PROSITE, PRINTS, Pfam, ProDom and SMART …