Adaptogens comprise a category of herbal medicinal and nutritional products promoting
adaptability, resilience, and survival of living organisms in stress. The aim of this review was …

To thrive and to fulfill their functions, cells need to maintain proteome homeostasis even in
the face of adverse environmental conditions or radical restructuring of the proteome during …

All cells count on precise mechanisms that regulate protein homeostasis to maintain a stable
and functional proteome. A progressive deterioration in the ability of cells to preserve the …

Proteins generally must fold into precise three-dimensional conformations to fulfill their
biological functions. In the cell, this fundamental process is aided by molecular chaperones …

Hormesis in aging is represented by mild stress-induced stimulation of protective
mechanisms in cells and organisms resulting in biologically beneficial effects. Single or …

Ageing is driven by the inexorable and stochastic accumulation of damage in biomolecules
vital for proper cellular function. Although this process is fundamentally haphazard and …

There exists a phenomenon in aging research whereby early life stress can have positive
impacts on longevity. The mechanisms underlying these observations suggest a robust, long …

Introduction Adaptogens are natural compounds or plant extracts that increase adaptability
and survival of organisms under stress. Adaptogens stimulate cellular and organismal …

The heat-shock response, one of the main pro-survival mechanisms of a living organism,
has evolved as the biochemical response of cells to cope with heat stress. The most well …

In the last decade or so, it has been realised that membranes do not just have a lipid-bilayer
structure in which proteins are embedded or with which they associate. Structures are …