Bacteria and host interactions in the gut epithelial barrier

H Ashida, M Ogawa, M Kim, H Mimuro… - Nature chemical …, 2012 - nature.com
The gut mucosa acts as a barrier against microbial invaders, whereas resident commensal
and foreign invading bacteria interact intimately with the gut epithelium and influence the …

Molecular Insights into Burkholderia pseudomallei and Burkholderia mallei Pathogenesis

EE Galyov, PJ Brett, D DeShazer - Annual review of …, 2010 - annualreviews.org
Burkholderia pseudomallei and Burkholderia mallei are closely related gram-negative
bacteria that can cause serious diseases in humans and animals. This review summarizes …

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

Y Zhao, J Yang, J Shi, YN Gong, Q Lu, H Xu, L Liu… - Nature, 2011 - nature.com
Inflammasomes are large cytoplasmic complexes that sense microbial infections/danger
molecules and induce caspase-1 activation-dependent cytokine production and …

Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family

J Cui, Q Yao, S Li, X Ding, Q Lu, H Mao, L Liu, N Zheng… - Science, 2010 - science.org
A family of bacterial effectors including Cif homolog from Burkholderia pseudomallei (CHBP)
and Cif from Enteropathogenic Escherichia coli (EPEC) adopt a functionally important …

Pathogenicity and virulence of Burkholderia pseudomallei

NM Bzdyl, CL Moran, J Bendo, M Sarkar-Tyson - Virulence, 2022 - Taylor & Francis
The soil saprophyte, Burkholderia pseudomallei, is the causative agent of melioidosis, a
disease endemic in South East Asia and northern Australia. Exposure to B. pseudomallei by …

[HTML][HTML] Strategies for Intracellular Survival of Burkholderia pseudomallei

EM Allwood, RJ Devenish, M Prescott, B Adler… - Frontiers in …, 2011 - frontiersin.org
Burkholderia pseudomallei is the causative agent of melioidosis, a disease with high
mortality that is prevalent in tropical regions of the world. A key component of the …

Exploitation of the host ubiquitin system by human bacterial pathogens

H Ashida, M Kim, C Sasakawa - Nature Reviews Microbiology, 2014 - nature.com
Ubiquitylation is a crucial post-translational protein modification that regulates several
cellular processes in eukaryotes, including inflammatory responses, endocytic trafficking …

[HTML][HTML] Structural basis of PcsB-mediated cell separation in Streptococcus pneumoniae

SG Bartual, D Straume, GA Stamsås, IG Muñoz… - Nature …, 2014 - nature.com
Separation of daughter cells during bacterial cell division requires splitting of the septal
cross wall by peptidoglycan hydrolases. In Streptococcus pneumoniae, PcsB is predicted to …

Insecticidal toxins from the Photorhabdus and Xenorhabdus bacteria

SJ Hinchliffe, MC Hares… - The Open Toxinology …, 2010 - benthamopen.com
Insect pathogens are an excellent source of novel insecticidal agents with proven toxicity. In
particular, bacteria from the genera Photorhabdus and Xenorhabdus are proving to be a …

Legionella pneumophila regulates the activity of UBE2N by deamidase‐mediated deubiquitination

N Gan, H Guan, Y Huang, T Yu, J Fu… - The EMBO …, 2020 - embopress.org
Abstract The Legionella pneumophila effector MavC induces ubiquitination of the E2
ubiquitin‐conjugating enzyme UBE 2N by transglutamination, thereby abolishing its function …