microRNA-dependent regulation of gene expression in GABAergic interneurons

KA Kołosowska, G Schratt, J Winterer - Frontiers in Cellular …, 2023 - frontiersin.org
Information processing within neuronal circuits relies on their proper development and a
balanced interplay between principal and local inhibitory interneurons within those circuits …

A novel spinal neuron connection for heat sensation

H Wang, W Chen, Z Dong, G Xing, W Cui, L Yao… - Neuron, 2022 - cell.com
Heat perception enables acute avoidance responses to prevent tissue damage and
maintain body thermal homeostasis. Unlike other modalities, how heat signals are …

[HTML][HTML] Progress on the hippocampal circuits and functions based on sharp wave ripples

B Xie, Z Zhen, O Guo, H Li, M Guo, J Zhen - Brain Research Bulletin, 2023 - Elsevier
Sharp wave ripples (SWRs) are high-frequency synchronization events generated by
hippocampal neuronal circuits during various forms of learning and reactivated during …

Energy expenditure homeostasis requires ErbB4, an obesity risk gene, in the paraventricular nucleus

I Santiago-Marrero, F Liu, H Wang, EP Arzola… - Eneuro, 2023 - eneuro.org
Obesity affects more than a third adult population in the United States; the prevalence is
even higher in patients with major depression disorders. GWAS studies identify the receptor …

ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer's disease mouse model

X Deng, X Liu, Y Wei, K Wang, J Zhu, J Zhong… - Acta Pharmacologica …, 2024 - nature.com
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer's disease
(AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the …

[HTML][HTML] NRG1-ErbB4 signaling in the medial amygdala controls mating motivation in adult male mice

J Huang, YY Zhang, YY Qiu, S Yao, WT Qiu, JL Peng… - Cell Reports, 2024 - cell.com
Motivation-driven mating is a basic affair for the maintenance of species. However, the
underlying molecular mechanisms that control mating motivation are not fully understood …

[HTML][HTML] Dynamic microglia alterations associate with hippocampal network impairments: A turning point in amyloid pathology progression

G Pizzirusso, E Preka, J Goikolea… - Brain, Behavior, and …, 2024 - Elsevier
Alzheimer's disease is a progressive neurological disorder causing memory loss and
cognitive decline. The underlying causes of cognitive deterioration and neurodegeneration …

[HTML][HTML] NRG1-ErbB4 signaling in the cerebrospinal fluid-contacting nucleus regulates thermal pain in mice

Y Ding, Y Yan, W Song, Y Li, J Zhao, B Gui, Y Zhang… - Neuroscience, 2025 - Elsevier
The cerebrospinal fluid-contacting nucleus (CSF-contacting nucleus) is a pair of unique
nuclei in the brain parenchyma which has long been demonstrated to play an important role …

ErbB4 processing is involved in OGD/R induced neuron injury

A Deng, S Wang, J Qin, P Yang, S Shen, H Zhou… - Journal of Stroke and …, 2023 - Elsevier
Objective Our previous study found that ErbB4 gene expression was changed after oxygen-
glucose deprivation/reperfusion (OGD/R). However, the exact role and mechanism of ErbB4 …

Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression

G Pizzirusso, E Preka, J Goikolea, C Aguilar-Ruiz… - bioRxiv, 2024 - biorxiv.org
Alzheimer's disease is a progressive neurological disorder causing memory loss and
cognitive decline. The underlying causes of cognitive deterioration and neurodegeneration …