Modern genome-scale methods that identify new genes, such as proteogenomics and
ribosome profiling, have revealed, to the surprise of many, that overlap in genes, open …

Small proteins encoded by open reading frames (ORFs) shorter than 50 codons (small
ORFs [sORFs]) are often overlooked by annotation engines and are difficult to characterize …

Small proteins consisting of 50 or fewer amino acids have been identified as regulators of
larger proteins in bacteria and eukaryotes. Despite the importance of these molecules, the …

The mesophilic methanogenic archaeal model organism Methanosarcina mazei strain Gö1
is crucial for climate and environmental research due to its ability to produce methane. Here …

The Freiburg RNA tools webserver is a well established online resource for RNA-focused
research. It provides a unified user interface and comprehensive result visualization for …

In contrast to extensively studied prokaryotic 'small'transcriptomes (encompassing all small
noncoding RNAs), small proteomes (here defined as including proteins≤ 70 aa) are only …

Small proteins encoded by short open reading frames (ORFs) with 50 codons or fewer are
emerging as an important class of cellular macromolecules in diverse organisms. However …

In recent years, increasing numbers of small proteins have moved into the focus of science.
Small proteins have been identified and characterized in all three domains of life, but the …

Many prokaryotic RNAs are transcribed from loci outside of annotated protein coding genes.
Across bacterial species hundreds of short open reading frames antisense to annotated …

Small open reading frames (smORFs) are widely distributed in various living organisms.
However, their functions remain largely unexplored. In addition, annotation and detection of …