Drawbacks of artificial intelligence and their potential solutions in the healthcare sector

B Khan, H Fatima, A Qureshi, S Kumar… - Biomedical Materials & …, 2023 - Springer
Artificial intelligence (AI) has the potential to make substantial progress toward the goal of
making healthcare more personalized, predictive, preventative, and interactive. We believe …

[HTML][HTML] Artificial intelligence in clinical health care applications

M Van Hartskamp, S Consoli, W Verhaegh… - Interactive journal of …, 2019 - i-jmr.org
The idea of artificial intelligence (AI) has a long history. It turned out, however, that reaching
intelligence at human levels is more complicated than originally anticipated. Currently, we …

Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways

GF van Wigcheren, J Cuenca-Escalona… - Journal of Biological …, 2023 - ASBMB
Imbalanced immune responses are a prominent hallmark of cancer and autoimmunity.
Myeloid cells can be overly suppressive, inhibiting protective immune responses or inactive …

Estrogen receptor pathway activity score to predict clinical response or resistance to neoadjuvant endocrine therapy in primary breast cancer

MA Inda, EJ Blok, PJK Kuppen, A Charehbili… - Molecular cancer …, 2020 - AACR
Endocrine therapy is important for management of patients with estrogen receptor (ER)–
positive breast cancer; however, positive ER staining does not reliably predict therapy …

[HTML][HTML] Multi-omic approaches to improve outcome for T-cell acute lymphoblastic leukemia patients

JCG van der Zwet, K Canté-Barrett… - Advances in Biological …, 2019 - Elsevier
In the last decade, tremendous progress in curative treatment has been made for T-ALL
patients using high-intensive, risk-adapted multi-agent chemotherapy. Further treatment …

[HTML][HTML] Adjuvant androgen deprivation therapy for poor-risk, androgen receptor–positive salivary duct carcinoma

W Van Boxtel, LD Locati… - European journal of …, 2019 - Elsevier
Aim Salivary duct carcinoma (SDC), an aggressive subtype of salivary gland cancer, is
androgen receptor (AR)–positive in 67–96% of cases. In patients with locally recurrent and …

[HTML][HTML] Case series of docetaxel, trastuzumab, and pertuzumab (DTP) as first line anti-HER2 therapy and ado-trastuzumab emtansine (T-DM1) as second line for …

MJM Uijen, G Lassche, ACH van Engen-van Grunsven… - Oral Oncology, 2022 - Elsevier
Objective Salivary duct carcinoma (SDC) overexpresses Human Epidermal growth factor
Receptor 2 (HER2) in 29–46% of cases, favoring anti-HER2 therapy. Here, we present the …

Prediction of clinical benefit from androgen deprivation therapy in salivary duct carcinoma patients

W van Boxtel, GW Verhaegh… - … journal of cancer, 2020 - Wiley Online Library
Androgen deprivation therapy (ADT) is first‐line palliative treatment in androgen receptor‐
positive (AR+) salivary duct carcinoma (SDC), and response rates are 17.6–50.0%. We …

TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signaling

PV Iyengar, DL Marvin, D Lama, TZ Tan… - Molecular Cancer …, 2022 - AACR
Patients with bladder cancer often have a poor prognosis due to the highly invasive and
metastatic characteristics of bladder cancer cells. Epithelial-to-mesenchymal transition …

Measurement of cellular immune response to viral infection and vaccination

W Bouwman, W Verhaegh, L Holtzer… - Frontiers in …, 2020 - frontiersin.org
Combined cellular and humoral host immune response determine the clinical course of a
viral infection and effectiveness of vaccination, but currently the cellular immune response …