Adaptive immune cells shape obesity-associated type 2 diabetes mellitus and less prominent comorbidities

S SantaCruz-Calvo, L Bharath, G Pugh… - Nature Reviews …, 2022 - nature.com
Obesity and type 2 diabetes mellitus (T2DM) are increasing in prevalence owing to
decreases in physical activity levels and a shift to diets that include addictive and/or high …

Obesity phenotypes and their paradoxical association with cardiovascular diseases

A Vecchié, F Dallegri, F Carbone… - European journal of …, 2018 - Elsevier
The pro-inflammatory state of the visceral adipose tissue (VAT) is supposed to accelerate
cardiovascular (CV) and metabolic diseases in obese subjects. Some studies have recently …

[HTML][HTML] Documento de información y consenso para la detección y manejo de la enfermedad renal crónica

R García-Maset, J Bover, JS de la Morena… - nefrologia, 2022 - Elsevier
La enfermedad renal crónica (ERC) es un importante problema de salud pública a nivel
mundial afectando a más del 10% de la población española. Se asocia a elevada …

Inflammation and premature aging in advanced chronic kidney disease

JP Kooman, MJ Dekker, LA Usvyat… - American Journal …, 2017 - journals.physiology.org
Systemic inflammation in end-stage renal disease is an established risk factor for mortality
and a catalyst for other complications, which are related to a premature aging phenotype …

The higher mortality associated with low serum albumin is dependent on systemic inflammation in end-stage kidney disease

FC Alves, J Sun, AR Qureshi, L Dai, S Snaedal… - PloS one, 2018 - journals.plos.org
Background The correlation of low serum albumin with mortality in patients with chronic
kidney disease (CKD) is partly linked to its association with systemic inflammation. However …

The dual roles of obesity in chronic kidney disease: a review of the current literature

CM Rhee, SF Ahmadi… - Current opinion in …, 2016 - journals.lww.com
In addition to its role as a risk factor for de novo CKD, there appears to be a consistent
association between obesity and lower mortality in those with established CKD, particularly …

Obesity paradox in advanced kidney disease: from bedside to the bench

N Naderi, CE Kleine, C Park, JT Hsiung… - Progress in …, 2018 - Elsevier
While obesity is associated with a variety of complications including diabetes, hypertension,
cardiovascular disease and premature death, observational studies have also found that …

Clinical global assessment of nutritional status as predictor of mortality in chronic kidney disease patients

L Dai, H Mukai, B Lindholm, O Heimbürger, P Barany… - PloS one, 2017 - journals.plos.org
Background The value of subjective global assessment (SGA) as nutritional assessor of
protein-energy wasting (PEWSGA) in chronic kidney disease (CKD) patients depends on its …

Associations of chronic inflammation, insulin resistance, and severe obesity with mortality, myocardial infarction, cancer, and chronic pulmonary disease

N Wiebe, P Stenvinkel, M Tonelli - JAMA network open, 2019 - jamanetwork.com
Importance Chronic inflammation and insulin resistance often accompany severe obesity,
and all are associated with disease risk. Objective To examine how the association of …

Clinical implications of fetuin-A

P Jirak, L Stechemesser, E Moré, M Franzen… - Advances in clinical …, 2019 - Elsevier
Fetuin-A, also termed alpha2-Heremans-Schmid glycoprotein, is a 46 kDa hepatocyte
derived protein (hepatokine) and serves multifaceted functions.(i) It acts as systemic inhibitor …