Direct trafficking pathways from the Golgi apparatus to the plasma membrane
D Stalder, DC Gershlick - Seminars in cell & developmental biology, 2020 - Elsevier
In eukaryotic cells, protein sorting is a highly regulated mechanism important for many
physiological events. After synthesis in the endoplasmic reticulum and trafficking to the Golgi …
physiological events. After synthesis in the endoplasmic reticulum and trafficking to the Golgi …
Multiple roles for actin in secretory and endocytic pathways
Actin filaments play multiple roles in the secretory pathway and in endosome dynamics in
mammals, including maintenance of Golgi structure, release of membrane cargo from the …
mammals, including maintenance of Golgi structure, release of membrane cargo from the …
Nutrient regulation of pancreatic islet β-cell secretory capacity and insulin production
KE Rohli, CK Boyer, SE Blom, SB Stephens - Biomolecules, 2022 - mdpi.com
Pancreatic islet β-cells exhibit tremendous plasticity for secretory adaptations that coordinate
insulin production and release with nutritional demands. This essential feature of the β-cell …
insulin production and release with nutritional demands. This essential feature of the β-cell …
How viruses hijack and modify the secretory transport pathway
Eukaryotic cells contain dynamic membrane-bound organelles that are constantly
remodeled in response to physiological and environmental cues. Key organelles are the …
remodeled in response to physiological and environmental cues. Key organelles are the …
Activity of the SPCA1 calcium pump couples sphingomyelin synthesis to sorting of secretory proteins in the trans-Golgi network
Y Deng, M Pakdel, B Blank, EL Sundberg, CG Burd… - Developmental cell, 2018 - cell.com
How the principal functions of the Golgi apparatus—protein processing, lipid synthesis, and
sorting of macromolecules—are integrated to constitute cargo-specific trafficking pathways …
sorting of macromolecules—are integrated to constitute cargo-specific trafficking pathways …
Cryo-EM structures of human SPCA1a reveal the mechanism of Ca2+/Mn2+ transport into the Golgi apparatus
Z Chen, S Watanabe, H Hashida, M Inoue… - Science …, 2023 - science.org
Secretory pathway Ca2+/Mn2+ ATPase 1 (SPCA1) actively transports cytosolic Ca2+ and
Mn2+ into the Golgi lumen, playing a crucial role in cellular calcium and manganese …
Mn2+ into the Golgi lumen, playing a crucial role in cellular calcium and manganese …
Sending out molecules from the TGN
BR Ramazanov, ML Tran, J von Blume - Current opinion in cell biology, 2021 - Elsevier
The sorting of secreted cargo proteins and their export from the trans-Golgi network (TGN)
remains an enigma in the field of membrane trafficking; although the sorting mechanisms of …
remains an enigma in the field of membrane trafficking; although the sorting mechanisms of …
Primary active Ca2+ transport systems in health and disease
J Chen, A Sitsel, V Benoy… - Cold Spring …, 2020 - cshperspectives.cshlp.org
Calcium ions (Ca2+) are prominent cell signaling effectors that regulate a wide variety of
cellular processes. Among the different players in Ca2+ homeostasis, primary active Ca2+ …
cellular processes. Among the different players in Ca2+ homeostasis, primary active Ca2+ …
Lipid‐dependent coupling of secretory cargo sorting and trafficking at the trans‐Golgi network
J von Blume, A Hausser - FEBS letters, 2019 - Wiley Online Library
In eukaryotic cells, the trans‐Golgi network (TGN) serves as a platform for secretory cargo
sorting and trafficking. In recent years, it has become evident that a complex network of lipid …
sorting and trafficking. In recent years, it has become evident that a complex network of lipid …