Retinitis Pigmentosa (RP) is a hereditary retinopathy that affects about 2.5 million people
worldwide. It is characterized with progressive loss of rods and cones and causes severe …

Inherited mutations in the rod visual pigment, rhodopsin, cause the degenerative blinding
condition, retinitis pigmentosa (RP). Over 150 different mutations in rhodopsin have been …

Glaucoma is a neurodegenerative disease of the eye and it is one of the leading causes of
blindness. Glaucoma is characterized by progressive degeneration of retinal ganglion cells …

The'bionic eye'—so long a dream of the future—is finally becoming a reality with retinal
prostheses available to patients in both the US and Europe. However, clinical experience …

Retinitis pigmentosa (RP) is a diverse group of hereditary degenerations characterized by
progressive dysfunction of predominantly rod followed by cone photoreceptors. Typical RP …

Glaucoma is one of the leading causes of vision loss in the world. Currently,
pharmacological intervention for glaucoma therapy is limited to eye drops that reduce …

Glaucoma is a neurodegenerative disease of the eye, which involves degeneration of retinal
ganglion cells (RGCs): the output neurons of the retina to the brain, which with their axons …

Epigenetic modifiers are increasingly being investigated as potential therapeutics to modify
and overcome disease phenotypes. Diseases of the nervous system present a particular …

Blindness arising from retinal or macular degeneration results in significant social, health
and economic burden. While approved treatments exist for neovascular ('wet') age-related …

Glycogen synthase kinase 3 (GSK3) is a key regulator of many cellular signaling processes
and performs a wide range of biological functions in the nervous system. Due to its central …