Here, we report the method for copper‐catalyzed N‐arylation of diverse oxadiazolones by
diaryliodonium salts under mild conditions in high yields (up to 92%) using available CuI as …

Herein, we develop a metal catalyst‐free protocol for O‐arylation of benzamide hydroxamate
esters. The chemoselective O‐versus N‐arylation of the amides was tuned by varying the …

An efficient and environmentally friendly one‐pot sequential synthesis of functionalized
nordazepam and a benzimidazoquinazoline analogue is reported, utilizing cobalt as the …

Two new series of tricyclic heterocycles, namely 5, 6-dihydro-4H-benzo [b][1, 2, 4] triazolo [1,
5-d][1, 4] diazepinium salts 10 and the related neutral, free bases 13 were synthesized from …

Triarylphosphines and phosphine oxides are one of the most important classes of
organophosphorus compounds. They are widely used in homogenous catalysis in various …

V teoretické části diplomové práce jsou rozebírány nejen syntetické postupy vedoucí ke
vzniku derivátů benzodiazepinu (BZD) a pyrrolobenzodiazepinu (PBD), ale i biologické …

This thesis focuses on developing SF5-substituted biologically active compounds or building
blocks, often using microwave synthesis. SF5 is a fluorine containing functional group that …