Clinical course and management of COVID-19 in the era of widespread population immunity

EA Meyerowitz, J Scott, A Richterman, V Male… - Nature Reviews …, 2024 - nature.com
The clinical implications of COVID-19 have changed since SARS-CoV-2 first emerged in
humans. The current high levels of population immunity, due to prior infection and/or …

Viral load in COVID-19 patients: implications for prognosis and vaccine efficacy in the context of emerging SARS-CoV-2 variants

SJR Silva, SC Lima, RC Silva, A Kohl, L Pena - Frontiers in Medicine, 2022 - frontiersin.org
The worldwide spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused an unprecedented public health crisis in the 21st century. As the pandemic …

Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19

KD Wick, A Leligdowicz, A Willmore, SA Carrillo… - Critical Care, 2022 - Springer
Abstract Background Studies quantifying SARS-CoV-2 have focused on upper respiratory
tract or plasma viral RNA with inconsistent association with clinical outcomes. The …

A comprehensive review of BBV152 vaccine development, effectiveness, safety, challenges, and prospects

F Dotiwala, AK Upadhyay - Frontiers in Immunology, 2022 - frontiersin.org
The world has responded to the COVID-19 pandemic with unprecedented speed and vigor
in the mass vaccination campaigns, targeted to reduce COVID-19 severity and mortality …

Longitudinally monitored immune biomarkers predict the timing of COVID-19 outcomes

G Lasso, S Khan, SA Allen, M Mariano… - PLOS Computational …, 2022 - journals.plos.org
The clinical outcome of SARS-CoV-2 infection varies widely between individuals. Machine
learning models can support decision making in healthcare by assessing fatality risk in …

Hospitalization, death, and probable reinfection in Peruvian healthcare workers infected with SARS-CoV-2: a national retrospective cohort study

W Ramos, N Guerrero, EO Napanga-Saldaña… - Human resources for …, 2022 - Springer
Background Peru has some of the worst outcomes worldwide as a result of the SARS-CoV-2
pandemic; it is presumed that this has also affected healthcare workers. This study aimed to …

High titers of neutralizing SARS-CoV-2 antibodies six months after symptom onset are associated with increased severity in COVID-19 hospitalized patients

A Sejdic, A Frische, CS Jørgensen, LD Rasmussen… - Virology journal, 2023 - Springer
Background Viral shedding and neutralizing antibody (NAb) dynamics among patients
hospitalized with severe coronavirus disease 2019 (COVID-19) and immune correlates of …

COVID-19 in patients with hematologic malignancies: clinical manifestations, persistence, and immune response

I Gur, A Giladi, YN Isenberg, A Neuberger… - Acta haematologica, 2022 - karger.com
Background: The clinical presentation of coronavirus disease 19 (COVID-19) is the result of
intricate interactions between the novel coronavirus and the immune system. In patients with …

Evaluating methodological approaches to assess the severity of infection with SARS-CoV-2 variants: scoping review and applications on Belgian COVID-19 data

M Meurisse, H Van Oyen, K Blot, L Catteau… - BMC infectious …, 2022 - Springer
Background Differences in the genetic material of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variants may result in altered virulence characteristics …

Predictors of SARS-CoV-2 RNA from nasopharyngeal swabs and concordance with other compartments in nonhospitalized adults with mild to moderate COVID-19

C Moser, JZ Li, JJ Eron, E Aga, ES Daar… - Open forum …, 2022 - academic.oup.com
Background Identifying characteristics associated with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) RNA shedding may be useful to understand viral …