Folliculogenesis is a complex process that requires integration of autocrine, paracrine, and
endocrine factors together with tightly regulated interactions between granulosa cells and …

In vitro ovarian follicle culture provides a tool to investigate folliculogenesis, and may one
day provide women with fertility-preservation options. The application of tissue engineering …

Oocytes grown in vitro are of low quality and yield few live births, thus limiting the ability to
store or bank the ova of women wishing to preserve their fertility. We applied tissue …

The availability of viable oocytes is the limiting factor in the development of new reproductive
techniques. Many attempts have been made to grow immature oocytes in vitro during recent …

BACKGROUND Ovarian tissue cryopreservation is a promising technique to safeguard
fertility in cancer patients. However, in some types of cancer, there is a risk of transmitting …

Sheep preantral follicles (PFs) measuring 250–400 μm in diameter were cultured for six
days in serum-free media supplemented differently with growth factors and hormones …

Although ovarian theca cells play an indispensable role in folliculogenesis by providing
follicular structural integrity and steroid substrates for estrogen production, little information …

BACKGROUND The aim of this study was to investigate the effect of sodium selenite (SS) on
reactive oxygen species (ROS) production, total antioxidant capacity (TAC) and glutathione …

Notch signaling is an evolutionarily conserved pathway, which regulates cell proliferation,
differentiation, and apoptosis. It has been reported that the members of Notch signaling are …

In the pharmaceutical industry, preclinical developmental and reproductive toxicity studies
are conducted in laboratory animals in order to predict and prevent adverse effects of drugs …