The cytokine IL-10 is a key anti-inflammatory mediator ensuring protection of a host from
over-exuberant responses to pathogens and microbiota, while playing important roles in …

Objective To present a comprehensive review of the association between measures of body
weight, waist, and fat, and different ratios of these measures, and the risk of type 2 diabetes …

The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D).
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …

Type 2 diabetes is a serious and common chronic disease resulting from a complex
inheritance-environment interaction along with other risk factors such as obesity and …

Accumulating evidence indicates that obesity is closely associated with an increased risk of
metabolic diseases such as insulin resistance, type 2 diabetes, dyslipidemia and …

Introduction: Metabolic syndrome represents a cluster of related metabolic abnormalities,
including central obesity, hypertension, dyslipidemia, hyperglycemia, and insulin resistance …

The most problematic issue in clinical nephrology is the relentless and progressive increase
in patients with ESRD (end-stage renal disease) worldwide. The impact of diabetic …

Obesity and associated chronic inflammation initiate a state of insulin resistance (IR). The
secretion of chemoattractants such as MCP-1 and MIF and of cytokines IL-6, TNF-α, and IL …

Weight gain and obesity are major risk factors for conditions and diseases ranging from
insulin resistance and type 2 diabetes mellitus to atherosclerosis and the sequelae of …

Obesity-induced chronic inflammation is a key component in the pathogenesis of insulin
resistance and the Metabolic syndrome. In this review, we focus on the interconnection …