Liquid biopsy in breast cancer: A comprehensive review
S Alimirzaie, M Bagherzadeh, MR Akbari - Clinical genetics, 2019 - Wiley Online Library
Breast cancer is the most common cancer among women worldwide. Due to its complexity in
nature, effective breast cancer treatment can encounter many challenges. Traditional …
nature, effective breast cancer treatment can encounter many challenges. Traditional …
Highlights in resistance mechanism pathways for combination therapy
Combination chemotherapy has been a mainstay in cancer treatment for the last 60 years.
Although the mechanisms of action and signaling pathways affected by most treatments with …
Although the mechanisms of action and signaling pathways affected by most treatments with …
Combination therapy and the evolution of resistance: the theoretical merits of synergism and antagonism in cancer
The search for effective combination therapies for cancer has focused heavily on synergistic
combinations because they exhibit enhanced therapeutic efficacy at lower doses. Although …
combinations because they exhibit enhanced therapeutic efficacy at lower doses. Although …
[HTML][HTML] Albumin metabolism targeted peptide-drug conjugate strategy for targeting pan-KRAS mutant cancer
Despite recent breakthroughs in the development of direct KRAS inhibitors and modulators,
no drugs targeting pan-KRAS mutant cancers are clinically available. Here, we report a …
no drugs targeting pan-KRAS mutant cancers are clinically available. Here, we report a …
Tumor microenvironment–selective pressures boosting cancer progression
SC Nunes - Tumor Microenvironment: The Main Driver of Metabolic …, 2020 - Springer
Abstract In 2018, 9.6 million deaths from cancer were estimated, being this disease the
second leading cause of death worldwide. Notwithstanding all the efforts developed in …
second leading cause of death worldwide. Notwithstanding all the efforts developed in …
Modelling inactivation of wild‐type and clinical Escherichia coli O26 strains using UV‐C and thermal treatment and subsequent persistence in simulated gastric fluid
Aims First, two inactivation models were compared for different phenotypic profiles of
Escherichia coli O26 using ultraviolet‐C light (UV‐C) and thermal treatment (T), by means of …
Escherichia coli O26 using ultraviolet‐C light (UV‐C) and thermal treatment (T), by means of …
Evolving paradigms on the interplay of mitochondrial Hsp70 chaperone system in cell survival and senescence
S Srivastava, V Vishwanathan, A Birje… - Critical Reviews in …, 2019 - Taylor & Francis
The role of mitochondria within a cell has grown beyond being the prime source of cellular
energy to one of the major signaling platforms. Recent evidence provides several insights …
energy to one of the major signaling platforms. Recent evidence provides several insights …
Impact of chemotherapy on the expression of claudins and cadherins in invasive breast cancer
H Skálová, N Hájková, B Majerová… - Experimental and …, 2019 - spandidos-publications.com
The importance of the expression profile of claudins in the molecular classification of breast
cancer (BC) is currently under investigation. Claudins, together with cadherins, serve an …
cancer (BC) is currently under investigation. Claudins, together with cadherins, serve an …
Essentiality, protein–protein interactions and evolutionary properties are key predictors for identifying cancer-associated genes using machine learning
The distinctive nature of cancer as a disease prompts an exploration of the special
characteristics the genes implicated in cancer exhibit. The identification of cancer …
characteristics the genes implicated in cancer exhibit. The identification of cancer …
Epigenetic mechanism of therapeutic resistance and potential of epigenetic therapeutics in chemorefractory prostate cancer
Prostate cancer is the second leading cause of cancer death among men in the United
States. Depending upon the histopathological subtypes of prostate cancers, various …
States. Depending upon the histopathological subtypes of prostate cancers, various …