Geographical spread and structural basis of sulfadoxine-pyrimethamine drug-resistant malaria parasites

R Chaturvedi, J Chhibber-Goel, I Verma… - International Journal for …, 2021 - Elsevier
The global spread of sulfadoxine (Sdx, S) and pyrimethamine (Pyr, P) resistance is attributed
to increasing number of mutations in DHPS and DHFR enzymes encoded by malaria …

High multiple mutations of Plasmodium falciparum-resistant genotypes to sulphadoxine-pyrimethamine in Lagos, Nigeria

H Quan, U Igbasi, W Oyibo, S Omilabu… - Infectious Diseases of …, 2020 - Springer
Background Plasmodium falciparum-resistance to sulphadoxine-pyrimethamine (SP) has
been largely reported among pregnant women. However, the profile of resistance markers to …

Molecular analysis of bio-makers of chloroquine resistance in Plasmodium falciparum isolate from Gombe local government area, Gombe State, Nigeria

I Muhammad, PM Sale, MK Salisu… - Cellular, Molecular …, 2022 - cmbr-journal.com
Chloroquine was one of the most cheapest and effective chemotherapeutic drugs for
Plasmodium falciparum-malaria, but for a long, the drug has been officially withdrawn in …

Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of …

MN Ikegbunam, CN Nkonganyi, BN Thomas… - Malaria Journal, 2019 - Springer
Background A reversal of chloroquine (CQ) resistance following a period of withdrawal has
raised the possibility of its re-introduction. This study evaluated the current prevalence of …

Geographical and temporal variation in reduction of malaria infection among children under 5 years of age throughout Nigeria

W Oyibo, G Ntadom, P Uhomoibhi, O Oresanya… - BMJ global …, 2021 - gh.bmj.com
Introduction Global progress in reducing malaria has stalled since 2015. Analysis of the
situation is particularly needed in Nigeria, the country with by far the largest share of the …

[HTML][HTML] Xeno-monitoring of molecular drivers of artemisinin and partner drug resistance in P. falciparum populations in malaria vectors across Cameroon

FN Nkemngo, LMJ Mugenzi, M Tchouakui… - Gene, 2022 - Elsevier
Background Monitoring of drug resistance in Plasmodium populations is crucial for malaria
control. This has primarily been performed in humans and rarely in mosquitoes where …

Increase in the prevalence of mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates collected from early to late …

E Ruizendaal, MC Tahita, RB Geskus, I Versteeg… - Malaria journal, 2017 - Springer
Background Pregnant women are a high-risk group for Plasmodium falciparum infections,
which may result in maternal anaemia and low birth weight newborns, among other adverse …

Molecular epidemiology and evolution of drug-resistant genes in the malaria parasite Plasmodium falciparum in southwestern Nigeria

MA Oboh, US Singh, HA Antony, D Ndiaye… - Infection, Genetics and …, 2018 - Elsevier
Malaria is an age-old disease of human kind living in the tropical and sub-tropical regions of
the globe, with Africa contributing the highest incidence of morbidity and mortality. Among …

Does mosquito mass-rearing produce an inferior mosquito?

DD Soma, H Maïga, W Mamai, NS Bimbile-Somda… - Malaria Journal, 2017 - Springer
Background The success of the sterile insect technique depends, among other things, on
continuous releases of sexually competitive sterile males within the target area. Several …

Surveillance of genetic variations associated with antimalarial resistance of Plasmodium falciparum isolates from returned migrant workers in Wuhan, Central China

Y Yao, K Wu, M Xu, Y Yang, Y Zhang… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
Antimalarial drug resistance developed in Plasmodium falciparum has become a problem
for malaria control. Evaluation of drug resistance is the first step for effective malaria control …