Myasthenia gravis (MG) is an autoimmune disease caused by antibodies which attack
receptors at the neuromuscular junction. One of the main difficulties in predicting the clinical …

The glucocorticoid receptor (GR) is an evolutionally conserved nuclear receptor superfamily
protein that mediates the diverse actions of glucocorticoids as a ligand-dependent …

Toll-like receptor (TLR)-mediated innate immune responses are critically involved in the
pathogenesis of myasthenia gravis (MG), an autoimmune disorder affecting neuromuscular …

Autoimmune Myasthenia gravis (MG) is a chronic neuromuscular disease mainly due to
antibodies against the acetylcholine receptor (AChR) at the neuromuscular junction that …

Multiple myeloma (MM) induced bone lesion is one of the most crippling characteristics, and
the MM secreted Dickkopf-1 (DKK1) has been reported to play important role in this …

Multiple myeloma (MM) is a common malignant hematological disease. Dysregulation of
microRNAs (miRNAs) in MM cells and bone marrow microenviroment has important impacts …

Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn's disease (CD).
Glucocorticoids (GCs) are the most effective treatment for moderate to severe active UC …

METHODS Based on APC expression profile, the related genome-wide mRNA expression,
microRNA (miRNA) expression, and methylation profile in GC, the relationship between …

microRNAs (miRNAs/miRs) are a class of single-stranded non-coding RNA molecules of 19–
24 nucleotides (nt) in length. They are widely expressed in animals, plants, bacteria and …

The synthesis and release of glucocorticoids in living organisms are related to their
response to unfavorable stressful conditions in order to maintain homeostatic functions and …