Chemoresistance in pancreatic cancer

S Zeng, M Pöttler, B Lan, R Grützmann… - International journal of …, 2019 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), generally known as pancreatic cancer (PC),
ranks the fourth leading cause of cancer-related deaths in the western world. While the …

Molecular profile of metastasis, cell plasticity and EMT in pancreatic cancer: a pre-clinical connection to aggressiveness and drug resistance

Z Guo, M Ashrafizadeh, W Zhang, R Zou… - Cancer and metastasis …, 2024 - Springer
The metastasis is a multistep process in which a small proportion of cancer cells are
detached from the colony to enter into blood cells for obtaining a new place for metastasis …

Metagenomic identification of microbial signatures predicting pancreatic cancer from a multinational study

N Nagata, S Nishijima, Y Kojima, Y Hisada, K Imbe… - Gastroenterology, 2022 - Elsevier
Background & Aims To identify gut and oral metagenomic signatures that accurately predict
pancreatic ductal carcinoma (PDAC) and to validate these signatures in independent …

[HTML][HTML] Addressing the challenges of pancreatic cancer: future directions for improving outcomes

M Hidalgo, S Cascinu, J Kleeff, R Labianca, JM Löhr… - Pancreatology, 2015 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC), which accounts for more than 90% of all
pancreatic tumours, is a devastating malignancy with an extremely poor prognosis, as …

Burden of pancreatic cancer along with attributable risk factors in Europe between 1990 and 2019, and projections until 2039

J Yu, X Yang, W He, W Ye - International journal of cancer, 2021 - Wiley Online Library
Projecting the burden of pancreatic cancer over time provides essential information to
effectively plan measures for its management and prevention. Here, we obtained data from …

Multicenter study of early pancreatic cancer in Japan

A Kanno, A Masamune, K Hanada, H Maguchi… - Pancreatology, 2018 - Elsevier
Abstract Background/Objectives The diagnosis of early-stage pancreatic ductal
adenocarcinoma (PDAC) is still challenging. We conducted a multicenter study to clarify the …

[HTML][HTML] Current status and progress of pancreatic cancer in China

QJ Lin, F Yang, C Jin, DL Fu - World Journal of Gastroenterology …, 2015 - ncbi.nlm.nih.gov
Cancer is currently one of the most important public health problems in the world. Pancreatic
cancer is a fatal disease with poor prognosis. As in most other countries, the health burden …

Pancreatic cancer: pathogenesis and diagnosis

V Goral - Asian Pacific journal of cancer prevention, 2015 - journal.waocp.org
Pancreatic cancer is a fatal malignancies which is predominantly seen in men and at
advanced age (40-85years) and has an aggressive course. Its frequency is gradually …

Mucins in pancreatic cancer and its microenvironment

S Kaur, S Kumar, N Momi, AR Sasson… - Nature reviews …, 2013 - nature.com
Pancreatic cancer remains a lethal malignancy with poor prognosis owing to therapeutic
resistance, frequent recurrence and the absence of treatment strategies that specifically …

Pancreatic cancer incidence trends: evidence from the Surveillance, Epidemiology and End Results (SEER) population-based data

VL Gordon-Dseagu, SS Devesa… - International journal …, 2018 - academic.oup.com
Background Annual pancreatic cancer incidence rates have been increasing. We examine
pancreatic cancer incidence trends by demographics and histologic type. Methods Data …