[HTML][HTML] A Comprehensive Review of Protein Biomarkers for Invasive Lung Cancer

A Mezentsev, M Durymanov, VA Makarov - Current Oncology, 2024 - mdpi.com
Invasion and metastasis are important hallmarks of lung cancer, and affect patients' survival.
Early diagnostics of metastatic potential are important for treatment management. Recent …

Allergy-associated biomarkers in early life identified by Omics techniques

E Zubeldia-Varela, MD Ibáñez-Sandín… - Frontiers in …, 2024 - frontiersin.org
The prevalence and severity of allergic diseases have increased over the last 30 years.
Understanding the mechanisms responsible for these diseases is a major challenge in …

[HTML][HTML] Mapping the Periostin splice isoforms in atopic dermatitis and an in vitro asthma model–A multi-platform analysis using mass spectrometry and RT-qPCR

CE Rusbjerg-Weberskov, AK Hollensen… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Periostin is a matricellular protein known to be alternatively spliced to produce ten isoforms
with a molecular weight of 78–91 kDa. Within the extracellular matrix, periostin attaches to …

[HTML][HTML] The Importance of Suppressing Pathological Periostin Splicing Variants with Exon 17 in Both Stroma and Cancer

K Shibata, N Koibuchi, F Sanada, N Katsuragi… - Cells, 2024 - pmc.ncbi.nlm.nih.gov
Background: Periostin (POSTN) is a type of matrix protein that functions by binding to other
matrix proteins, cell surface receptors, or other molecules, such as cytokines and proteases …

Periostin Is a Disulfide-Bonded Homodimer and Forms a Complex with Fibronectin in the Human Skin

CE Rusbjerg-Weberskov, C Scavenius, JJ Enghild… - Biochemistry, 2024 - ACS Publications
The protein periostin is a matricellular protein that is expressed in connective tissue. It is
composed of five globular domains arranged in an elongated structure with an extensive …

Development of a top-down MS assay for specific identification of human periostin isoforms

CE Rusbjerg-Weberskov, MS Gant… - Frontiers in Molecular …, 2024 - frontiersin.org
Periostin is a matricellular protein encoded by the POSTN gene that is alternatively spliced
to produce ten different periostin isoforms with molecular weights ranging from 78 to 91 kDa …

Targeted Antisense Oligonucleotide-Mediated Skipping of Murine Postn Exon 17 Partially Addresses Fibrosis in D2.mdx Mice

J Trundle, N Lu-Nguyen, A Malerba… - International Journal of …, 2024 - mdpi.com
Periostin, a multifunctional 90 kDa protein, plays a pivotal role in the pathogenesis of fibrosis
across various tissues, including skeletal muscle. It operates within the transforming growth …