The ketogenic diet (KD) has been used as a treatment for epilepsy since the 1920s, and its
role in the prevention of many other diseases is now being considered. In recent years, there …

The advent of epigenetics brought in a tectonic shift in the understanding of molecular basis
of complex diseases like ischemic stroke (IS). Substantial scientific inquiry into the …

High-throughput single-cell epigenomic assays can resolve cell type heterogeneity in
complex tissues, however, spatial orientation is lost. Here, we present single-cell …

Accumulating evidence indicates a central role for epigenetic modifications in the
progression of stroke pathology. These epigenetic mechanisms are involved in complex and …

Despite the advancements in medical sciences in last few decades, we are yet to develop
promising therapeutics for stroke, which is one of the current global non-communicative …

Cessation of blood flow leads to a complex cascade of pathophysiological events at the
blood-vascular-parenchymal interface which evolves over time and space, and results in …

Cerebral ischemic stroke is one of the foremost global causes of death and disability. Due to
inadequate knowledge in its sequential disease mechanisms, therapeutic efforts to mitigate …

Epigenetic enzyme-targeted therapy is a promising new development in the field of drug
discovery. To date, histone deacetylases and DNA methyltransferases have been …

It has been confirmed that BTB domain and CNC homologue 1 (BACH1) are involved in
ferroptosis‐related diseases. However, the function of BACH1 in cerebral ischemia …

A wide plethora of intervention procedures, tissue plasminogen activators, mechanical
thrombectomy, and several neuroprotective drugs were reported in stroke research over the …