Power to the protein: enhancing and combining activities using the Spy toolbox

AH Keeble, M Howarth - Chemical Science, 2020 - pubs.rsc.org
Proteins span an extraordinary range of shapes, sizes and functionalities. Therefore generic
approaches are needed to overcome this diversity and stream-line protein analysis or …

Chemical and enzymatic methods for post-translational protein–protein conjugation

RJ Taylor, MB Geeson, T Journeaux… - Journal of the …, 2022 - ACS Publications
Fusion proteins play an essential role in the biosciences but suffer from several key
limitations, including the requirement for N-to-C terminal ligation, incompatibility of …

Signalling dynamics in embryonic development

KF Sonnen, CY Janda - Biochemical Journal, 2021 - portlandpress.com
In multicellular organisms, cellular behaviour is tightly regulated to allow proper embryonic
development and maintenance of adult tissue. A critical component in this control is the …

Molecular architecture and modifications of full-length myocilin

MD Martin, DJE Huard, RC Guerrero-Ferreira… - Experimental eye …, 2021 - Elsevier
Myocilin, a modular multidomain protein, is expressed broadly in the human body but is best
known for its presence in the trabecular meshwork extracellular matrix, and myocilin …

Gene Co-Expression Analysis of Human RNASEH2A Reveals Functional Networks Associated with DNA Replication, DNA Damage Response, and Cell Cycle …

S Marsili, A Tichon, D Kundnani, F Storici - Biology, 2021 - mdpi.com
Simple Summary RNASEH2A is the catalytic subunit of the ribonuclease (RNase) H2 ternary
complex that plays an important role in maintaining DNA stability in cells. Recent studies …

Expression of Rhizobium tropici phytochelatin synthase in Escherichia coli resulted in increased bacterial selenium nanoparticle synthesis

Q Yuan, M Bomma, H Hill, Z Xiao - Journal of Nanoparticle Research, 2020 - Springer
Phytochelatins are the main heavy metal detoxifying peptides found in plants. In the present
study, Escherichia coli DH5α cells were transformed with the phytochelatin synthase gene …