Integrons: past, present, and future
MR Gillings - Microbiology and molecular biology reviews, 2014 - Am Soc Microbiol
Integrons are versatile gene acquisition systems commonly found in bacterial genomes.
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …
Integrons: agents of bacterial evolution
D Mazel - Nature Reviews Microbiology, 2006 - nature.com
Integrons are assembly platforms—DNA elements that acquire open reading frames
embedded in exogenous gene cassettes and convert them to functional genes by ensuring …
embedded in exogenous gene cassettes and convert them to functional genes by ensuring …
Prevalence and characterisation of antimicrobial resistance genes and class 1 and 2 integrons in multiresistant Escherichia coli isolated from poultry production
P Racewicz, M Majewski, H Biesiada… - Scientific Reports, 2022 - nature.com
A global increase in the populations of drug resistant bacteria exerts negative effects on
animal production and human health. Our study has been focused on the assessment of …
animal production and human health. Our study has been focused on the assessment of …
Integrons: mobilizable platforms that promote genetic diversity in bacteria
Integrons facilitate the capture of potentially adaptive exogenous genetic material by their
host genomes. It is now clear that integrons are not limited to the clinical contexts in which …
host genomes. It is now clear that integrons are not limited to the clinical contexts in which …
The integron/gene cassette system: an active player in bacterial adaptation
The integron includes a site-specific recombination system capable of integrating and
expressing genes contained in structures called mobile gene cassettes. Integrons were …
expressing genes contained in structures called mobile gene cassettes. Integrons were …
Prevalence of SOS-mediated control of integron integrase expression as an adaptive trait of chromosomal and mobile integrons
Background Integrons are found in hundreds of environmental bacterial species, but are
mainly known as the agents responsible for the capture and spread of antibiotic-resistance …
mainly known as the agents responsible for the capture and spread of antibiotic-resistance …
Probing the mobilome: discoveries in the dynamic microbiome
VR Carr, A Shkoporov, C Hill, P Mullany… - Trends in Microbiology, 2021 - cell.com
There has been an explosion of metagenomic data representing human, animal, and
environmental microbiomes. This provides an unprecedented opportunity for comparative …
environmental microbiomes. This provides an unprecedented opportunity for comparative …
The genomic code: inferring Vibrionaceae niche specialization
FJ Reen, S Almagro-Moreno, D Ussery… - Nature Reviews …, 2006 - nature.com
The Vibrionaceae show a wide range of niche specialization, from free-living forms to those
attached to biotic and abiotic surfaces, from symbionts to pathogens and from estuarine …
attached to biotic and abiotic surfaces, from symbionts to pathogens and from estuarine …
A recalibrated molecular clock and independent origins for the cholera pandemic clones
Cholera, caused by Vibrio cholerae, erupted globally from South Asia in 7 pandemics, but
there were also local outbreaks between the 6th (1899–1923) and 7th (1961–present) …
there were also local outbreaks between the 6th (1899–1923) and 7th (1961–present) …
Diversity and evolution of the small multidrug resistance protein family
Background Members of the small multidrug resistance (SMR) protein family are integral
membrane proteins characterized by four α-helical transmembrane strands that confer …
membrane proteins characterized by four α-helical transmembrane strands that confer …