Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

Zinc finger proteins (ZNF) are among the most abundant proteins in eukaryotic genomes. It
contains several zinc finger domains that can selectively bind to certain DNA or RNA and …

Blood–brain barrier (BBB) breakdown after ischemic stroke exacerbates brain injury and
BBB senescence can cause severe neurological deficits in aged ischemic stroke population …

Background: Cerebral small vessel disease (CSVD) is a group of clinical syndromes
covering all pathological processes of small vessels in the brain, which can cause stroke …

Background: Increasing evidence suggests that acute traumatic spinal cord injury (SCI)-
induced defects in autophagy and autophagy-lysosomal pathway (ALP) may contribute to …

The disruption of the blood–brain barrier (BBB) plays a critical role in the pathology of
ischemic stroke. p75 neurotrophin receptor (p75NTR) contributes to the disruption of the …

Blood–brain barrier (BBB) breakdown, a characteristic feature of ischemic stroke, contributes
to poor patient outcomes. Brain microvascular endothelial cells (BMVECs) are a key …

Cerebrovascular disease is the most common life-threatening and debilitating condition that
often leads to stroke. The multifunctional calcium/calmodulin-dependent protein kinase II …

Background The long-term functional recovery of traumatic brain injury (TBI) is hampered by
pathological events, such as parenchymal neuroinflammation, neuronal death, and white …

Clinical studies have shown that dexmedetomidine (DEX) reduces mortality and
inflammation in patients with sepsis, and ameliorates cognitive decline in both postoperative …