Oxidative stress: The core pathogenesis and mechanism of Alzheimer's disease

R Bai, J Guo, XY Ye, Y Xie, T Xie - Ageing research reviews, 2022 - Elsevier
As the number of patients with Alzheimer's disease (AD) increases, it brings great suffering
to their families and causes a heavy socioeconomic burden to society. A vast amount of …

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

HJ Forman, H Zhang - Nature Reviews Drug Discovery, 2021 - nature.com
Oxidative stress is a component of many diseases, including atherosclerosis, chronic
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …

Red emissive carbon dot superoxide dismutase nanozyme for bioimaging and ameliorating acute lung injury

C Liu, W Fan, WX Cheng, Y Gu, Y Chen… - Advanced Functional …, 2023 - Wiley Online Library
Harnessing the physiochemical properties and enzymatic activities of nanozymes will
provide new insights for disease theranostics. Herein, a novel carbon dot (C‐dot) …

Antioxidant therapy in cancer: rationale and progress

M Luo, L Zhou, Z Huang, B Li, EC Nice, J Xu, C Huang - Antioxidants, 2022 - mdpi.com
Cancer is characterized by increased oxidative stress, an imbalance between reactive
oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of …

Combined antioxidant–antibiotic treatment for effectively healing infected diabetic wounds based on polymer vesicles

T Wang, Y Li, EJ Cornel, C Li, J Du - ACS nano, 2021 - ACS Publications
Infected diabetic wounds are difficult to heal due to high reactive oxygen species (ROS)
concentrations and recurrent infections. Such wounds can easily deteriorate into a diabetic …

Superoxide dismutase administration: A review of proposed human uses

AC Rosa, D Corsi, N Cavi, N Bruni, F Dosio - Molecules, 2021 - mdpi.com
Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …

Insights into manganese superoxide dismutase and human diseases

M Liu, X Sun, B Chen, R Dai, Z Xi, H Xu - International Journal of …, 2022 - mdpi.com
Redox equilibria and the modulation of redox signalling play crucial roles in physiological
processes. Overproduction of reactive oxygen species (ROS) disrupts the body's antioxidant …

The involvement of the oxidative stress status in cancer pathology: a double view on the role of the antioxidants

KF Zahra, R Lefter, A Ali, EC Abdellah… - Oxidative Medicine …, 2021 - Wiley Online Library
Oxygen‐free radicals, reactive oxygen species (ROS) or reactive nitrogen species (RNS),
are known by their “double‐sided” nature in biological systems. The beneficial effects of …

Natural antioxidant evaluation: A review of detection methods

JS Mendonça, RCA Guimarães, VA Zorgetto-Pinheiro… - Molecules, 2022 - mdpi.com
Antioxidants have drawn the attention of the scientific community due to being related to the
prevention of various degenerative diseases. The antioxidant capacity has been extensively …

The role of oxidative stress in the development of knee osteoarthritis: A comprehensive research review

L Liu, P Luo, M Yang, J Wang, W Hou… - Frontiers in molecular …, 2022 - frontiersin.org
Knee osteoarthritis (KOA) is one of the most common degenerative diseases, and its core
feature is the degeneration and damage of articular cartilage. The cartilage degeneration of …