The Baltimore classification of viruses 50 years later: how does it stand in the light of virus evolution?

EV Koonin, M Krupovic, VI Agol - Microbiology and Molecular …, 2021 - Am Soc Microbiol
SUMMARY Fifty years ago, David Baltimore published a brief conceptual paper delineating
the classification of viruses by the routes of genome expression. The six “Baltimore classes” …

Origins and evolutionary consequences of ancient endogenous retroviruses

WE Johnson - Nature Reviews Microbiology, 2019 - nature.com
Retroviruses infect a broad range of vertebrate hosts that includes amphibians, reptiles, fish,
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …

Origins and evolution of the global RNA virome

YI Wolf, D Kazlauskas, J Iranzo, A Lucía-Sanz, JH Kuhn… - MBio, 2018 - Am Soc Microbiol
Viruses with RNA genomes dominate the eukaryotic virome, reaching enormous diversity in
animals and plants. The recent advances of metaviromics prompted us to perform a detailed …

Origin of viruses: primordial replicators recruiting capsids from hosts

M Krupovic, VV Dolja, EV Koonin - Nature Reviews Microbiology, 2019 - nature.com
Viruses are ubiquitous parasites of cellular life and the most abundant biological entities on
Earth. It is widely accepted that viruses are polyphyletic, but a consensus scenario for their …

Silencing and transcriptional regulation of endogenous retroviruses: an overview

FK Geis, SP Goff - Viruses, 2020 - mdpi.com
Almost half of the human genome is made up of transposable elements (TEs), and about 8%
consists of endogenous retroviruses (ERVs). ERVs are remnants of ancient exogenous …

Viruses defined by the position of the virosphere within the replicator space

EV Koonin, VV Dolja, M Krupovic… - … and Molecular Biology …, 2021 - Am Soc Microbiol
Originally, viruses were defined as miniscule infectious agents that passed through filters
that retain even the smallest cells. Subsequently, viruses were considered obligate …

The global virome: How much diversity and how many independent origins?

EV Koonin, M Krupovic, VV Dolja - Environmental Microbiology, 2023 - Wiley Online Library
Viruses are considered to be the most abundant biological entities on earth. They also
display striking genetic diversity as emphatically demonstrated by the recent advances of …

Multiple origins of prokaryotic and eukaryotic single-stranded DNA viruses from bacterial and archaeal plasmids

D Kazlauskas, A Varsani, EV Koonin… - Nature …, 2019 - nature.com
Single-stranded (ss) DNA viruses are a major component of the earth virome. In particular,
the circular, Rep-encoding ssDNA (CRESS-DNA) viruses show high diversity and …

Global organization and proposed megataxonomy of the virus world

EV Koonin, VV Dolja, M Krupovic… - Microbiology and …, 2020 - Am Soc Microbiol
Viruses and mobile genetic elements are molecular parasites or symbionts that coevolve
with nearly all forms of cellular life. The route of virus replication and protein expression is …

Double-stranded RNA sequencing reveals distinct riboviruses associated with thermoacidophilic bacteria from hot springs in Japan

S Urayama, A Fukudome, M Hirai, T Okumura… - Nature …, 2024 - nature.com
Metatranscriptome sequencing expanded the known diversity of the bacterial RNA virome,
suggesting that additional riboviruses infecting bacterial hosts remain to be discovered …