Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of the blastocyst.
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …

Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs), and induced PSCs
(iPSCs) are able to self-renew and differentiate into a multitude of specialized cellular …

As cancer stem cells (CSCs) contribute to malignancy, metastasis, and relapse of cancers,
potential of compound in inhibition of CSCs has garnered most attention in the cancer …

Epithelial ovarian cancer (EOC) is the deadliest gynecologic cancer. Recently, the existence
of ovarian cancer stem cells has been reported. Sox2, Nanog and Oct4 are key markers of …

Natriuretic peptide signaling has been implicated in a broad range of physiological
processes, regulating blood volume and pressure, ventricular hypertrophy, fat metabolism …

Brain natriuretic peptide (BNP) contributes to heart formation during embryogenesis. After
birth, despite a high number of studies aimed at understanding by which mechanism (s) …

Embryonic stem (ES) cells are originated from the inner cell mass of a blastocyst stage
embryo. They can proliferate indefinitely, maintain an undifferentiated state (self-renewal) …

Mouse embryonic stem cells (ESCs) express high levels of cytoplasmic p53. Exposure of
mouse ESCs to DNA damage leads to activation of p53, inducing Nanog suppression. In …

Atrial natriuretic peptide (ANP) and brain NP (BNP) belong to the NP family that regulates
mammalian blood volume and blood pressure. ANP signaling through NP receptor A (NPR …

This review summarizes recent advances in understanding the role of the nitric oxide (NO)
and cyclic GMP (cGMP) pathway in stem cells. The levels of expression of various …