Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by
prolonged hyperglycemia that leads to long-term health consequences. It is estimated that …

Accelerating growth and global expansion of antimicrobial resistance has deepened the
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …

Antimicrobial peptides (AMPs) or host defense peptides protect the host against various
pathogens such as yeast, fungi, viruses and bacteria. AMPs also display immunomodulatory …

As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair
not only as structural cells but also exerting important immune functions. This review focuses …

Alarming data about increasing resistance to conventional antibiotics are reported, while at
the same time the development of new antibiotics is stagnating. Skin and soft tissue …

Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …

Wound healing is a well-orchestrated process, where numerous factors are activated or
inhibited in a sequence of steps. Immediately after the infliction of damage, the repair of …

Acute wound healing is an orderly process of four overlapping events: haemostasis,
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …

Diabetic patients often have ulcers on their lower-limbs that are infected by multiple biofilm-
forming genera of bacteria, and the elimination of the biofilm has proven highly successful in …

Gestational Diabetes Mellitus (GDM) is a transitory metabolic condition caused by
dysregulation triggered by intolerance to carbohydrates, dysfunction of beta-pancreatic and …