Pulmonary arterial hypertension nanotherapeutics: New pharmacological targets and drug delivery strategies

H Boucetta, L Zhang, A Sosnik, W He - Journal of Controlled Release, 2024 - Elsevier
Pulmonary arterial hypertension (PAH) is a rare, serious, and incurable disease
characterized by high lung pressure. PAH-approved drugs based on conventional pathways …

Oral administration of Huanglian-Houpo herbal nanoemulsion loading multiple phytochemicals for ulcerative colitis therapy in mice

X Wang, L Fu, W Cheng, J Chen, H Zhang, H Zhu… - Drug Delivery, 2023 - Taylor & Francis
How to achieve stable co-delivery of multiple phytochemicals is a common problem. This
study focuses on the development, optimization and characterization of Huanglian-HouPo …

Self-nanoemulsifying drug delivery system (SNEDDS) of docetaxel and carvacrol synergizes the anticancer activity and enables safer toxicity profile: optimization, and …

MAM Ateeq, M Aalhate, S Mahajan, GS Kumar… - Drug Delivery and …, 2023 - Springer
Docetaxel (DTX) is a first-line chemotherapeutic molecule with a broad-spectrum anticancer
activity. On the other hand, carvacrol (CV) has anti-inflammatory, antioxidant, cytotoxic, and …

Nanotechnology-based drug delivery platforms for erectile dysfunction: addressing efficacy, safety, and bioavailability concerns

VM Hari Priya, A Ganapathy A, MG Veeran… - Pharmaceutical …, 2024 - Taylor & Francis
Erectile dysfunction (ED), is a common and multidimensional sexual disorder, which
comprises changes among any of the processes of the erectile response such as organic …

Exploring the therapeutic potential of functional excipient-based nanoemulgel of fluticasone propionate for the management of psoriasis

S Jain, V Pattewad, N Bhargavi, S Yadav… - Journal of Drug Delivery …, 2023 - Elsevier
The current investigation deals with development of nanoemulsion based gel ie,
nanoemulgel utilizing bioactive excipients for the topical delivery of fluticasone propionate …

Enhancing oral bioavailability of dasatinib via supersaturable SNEDDS: Investigation of precipitation inhibition and IVIVC through in-vitro lipolysis-permeation model

D Mageshvaran, S Yadav, V Yadav, K Kuche… - International Journal of …, 2025 - Elsevier
Dasatinib (DASA), a potent second-generation multitarget kinase inhibitor marketed as
Sprycel®(Tablet), is limited by poor oral bioavailability (14–24%) and dose-related …

Self-Nanoemulsifying/Self-Assembled Cubic Nanoparticles Lyophilized Tablet: A Novel Biphasic Release Approach to Enhance the Bioavailability of a Lipophilic Drug

MM Farag, W El-Sebaie, EB Basalious… - AAPS …, 2024 - Springer
This study aimed to prepare a combined self-nanoemulsifying and self-assembled cubic
nanoparticles (SNE/SAC) lyophilized tablet eliciting biphasic release pattern escorted with …

Phyto-Nanoemulsion Containing Tea Leaves Extract Incorporated into A Hydrogel-Based Peel-Off Mask Formulation: Development, Antioxidant Assay, and Ex-Vivo …

DSC Wahyuni, RP Ferbinasari, S Sakinah… - Pharmaceutical …, 2023 - ps.tbzmed.ac.ir
Background: Tea leaves contain remarkable antioxidant compounds suitable for cosmetics
formulation development targeting anti-aging purposes. However, due to its hydrophilicity, it …

[PDF][PDF] Enhancement of Icariin Aphrodisiac Effect by Solid-SNEDDS Method Using

S Indratmoko, LH Nurani… - Journal of Advanced …, 2023 - eprints.uad.ac.id
Abstract The Epimedium brevicornu Maxim plant contains icariin, a flavonoid compound
known for its aphrodisiac effects. However, icariin has low solubility and bioavailability. This …