Chronic kidney disease (CKD) is the leading complication in type 2 diabetes (T2D) and
current therapies that limit CKD progression and the development of cardiovascular disease …

The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …

Prompted by the observation that atherosclerotic plaques from human diabetic subjects
displayed lower amounts of NADPH (nicotinamide adenine dinucleotide phosphate) …

Background: As the population grows older, the incidence and prevalence of conditions that
lead to a predisposition for poor wound healing also increase. Ultimately, this increase in …

Nowadays, there has been an increase in the number of people with chronic wounds, which
has resulted in serious health problems worldwide. The rate-limiting stage of chronic wound …

e160 Arterioscler Thromb Vasc Biol September 2018 were actively exported to the
cytoplasm with exportin-5 in a Ran-GTP–dependent manner. In the cytoplasm, the transition …

Diabetic foot ulcers (DFUs) are associated with complex pathogenic factors and are
considered a serious complication of diabetes. The potential mechanisms underlying DFUs …

Type 2 diabetes mellitus (T2DM), accounting for 90–95% cases of diabetes, is characterized
by chronic inflammation. The mechanisms that control inflammation activation in T2DM are …

Chronic, low-grade systemic inflammation and impaired microvascular function are critical
hallmarks in the development of insulin resistance. Accordingly, insulin resistance is a major …

Ethnopharmacological relevance Baicalin (BI) is an important biologically active flavonoid
isolated from the root of Scutellaria radix (Huang Qin). Traditionally Scutellaria radix was the …