Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses

L Belbasis, V Bellou, E Evangelou… - The Lancet …, 2015 - thelancet.com
Background The cause of multiple sclerosis is believed to involve environmental exposure
and genetic susceptibility. We aimed to summarise the environmental risk factors that have …

Modulation of the immune system by UV radiation: more than just the effects of vitamin D?

PH Hart, S Gorman, JJ Finlay-Jones - Nature Reviews Immunology, 2011 - nature.com
Humans obtain most of their vitamin D through the exposure of skin to sunlight. The
immunoregulatory properties of vitamin D have been demonstrated in studies showing that …

Smoking: effects on multiple sclerosis susceptibility and disease progression

DM Wingerchuk - Therapeutic advances in neurological …, 2012 - journals.sagepub.com
Multiple sclerosis (MS) is associated with both genetic and environmental factors that
influence disease susceptibility. Exposure to cigarette smoke is emerging as a viable …

Avoidance of sun exposure as a risk factor for major causes of death: a competing risk analysis of the Melanoma in Southern Sweden cohort

PG Lindqvist, E Epstein, K Nielsen… - Journal of internal …, 2016 - Wiley Online Library
Objective Women with active sunlight exposure habits experience a lower mortality rate than
women who avoid sun exposure; however, they are at an increased risk of skin cancer. We …

The association of diet with quality of life, disability, and relapse rate in an international sample of people with multiple sclerosis

EJ Hadgkiss, GA Jelinek, TJ Weiland… - Nutritional …, 2015 - Taylor & Francis
Objectives To explore the association between dietary factors including fat, fruit and
vegetable intake, dairy and meat consumption, and health-related quality of life (HRQOL) …

Clinically significant fatigue: prevalence and associated factors in an international sample of adults with multiple sclerosis recruited via the internet

TJ Weiland, GA Jelinek, CH Marck, EJ Hadgkiss… - PloS one, 2015 - journals.plos.org
Background Fatigue contributes a significant burden of disease for people with multiple
sclerosis (PwMS). Modifiable lifestyle factors have been recognized as having a role in a …

Factors associated with onset, relapses or progression in multiple sclerosis: a systematic review

KA McKay, S Jahanfar, T Duggan, S Tkachuk… - Neurotoxicology, 2017 - Elsevier
Multiple sclerosis (MS) is a chronic disease of the central nervous system with an
unidentified etiology. We systematically reviewed the literature on the possible risk factors …

Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity

J Breuer, N Schwab… - Annals of …, 2014 - Wiley Online Library
Objective Environmental conditions (eg, latitude) play a critical role in the susceptibility and
severity of many autoimmune disorders, including multiple sclerosis (MS). Here, we …

Multiple sclerosis and smoking

B Arneth - The American journal of medicine, 2020 - Elsevier
Multiple sclerosis (MS) is a common, severe neurological disease that affects millions of
people worldwide. Nevertheless, the actual cause of MS remains unknown. Smoking has …

Role of environmental factors in multiple sclerosis

A Zarghami, Y Li, SB Claflin, I van der Mei… - Expert Review of …, 2021 - Taylor & Francis
Introduction Environmental factors play a significant role in the pathogenesis and
progression of multiple sclerosis (MS), either acting alone or by interacting with other …