Irrespective of the reason for hypoperfusion, hypocoagulable and/or hyperfibrinolytic
hemostatic aberrancies afflict up to one-quarter of critically ill patients in shock. Intensivists …

Almost two-thirds of patients with severe traumatic brain injury (TBI) develop some form of
hemostatic disturbance, which contributes to poor outcome. While the initial head injury …

Introduction: Neutrophil-lymphocyte count ratio (NLCR) is a simple and low-cost marker of
inflammatory response. NLCR has shown to be a sensitive marker of clinical severity in …

A unique coagulopathy often manifests following traumatic brain injury, leading the clinician
down a difficult decision path on appropriate prophylaxis and therapy. Conventional …

OBJECTIVE Hematological abnormalities after severe traumatic brain injury (TBI) are
common, and are associated with a poor outcome. Whether these abnormalities offer …

Objective: Platelet inhibition in traumatic brain injury (TBI) may be due to injury or antiplatelet
medication use pre-injury. This study aims to identify factors associated with increased …

Coagulopathy is a known sequela of traumatic brain injury (TBI) and can lead to increased
morbidity and mortality. Platelet dysfunction has been identified as one of several etiologies …

Despite improvements in medical triage and tertiary care, traumatic brain injury (TBI)
remains associated with significant morbidity and mortality. Almost two-thirds of patients with …

Background: Because of the aging population, the number of low falls in elderly people with
pre-existing anticoagulation is rising, often leading to traumatic brain injury (TBI) with a …

Patients frequently visit the emergency department with conditions that place them at risk of
worse outcomes when accompanied by coagulopathy. Routine tests of coagulation …