Lifestyle medicine as a treatment for resistant hypertension

F Ribeiro, M Teixeira, AJ Alves, A Sherwood… - Current hypertension …, 2023 - Springer
Abstract Purpose of Review Approximately 10% of the adults with hypertension fail to
achieve the recommended blood pressure treatment targets on 3 antihypertensive …

Endoplasmic reticulum stress in systemic lupus erythematosus and lupus nephritis: potential therapeutic target

HY Li, LF Huang, XR Huang, D Wu… - Journal of …, 2023 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Approximately one‐
third to two‐thirds of the patients with SLE progress to lupus nephritis (LN). The …

Male kidney-specific BMAL1 knockout mice are protected from K+-deficient, high-salt diet-induced blood pressure increases

GR Crislip, HM Costello, A Juffre… - American Journal …, 2023 - journals.physiology.org
The circadian clock protein basic helix-loop-helix aryl hydrocarbon receptor nuclear
translocator-like protein 1 (BMAL1) is a transcription factor that impacts kidney function …

Subdiaphragmatic vagal nerve stimulation attenuates the development of hypertension and alters nucleus of the solitary tract transcriptional networks in the …

EW Dirr, LG Jiracek, DM Baekey… - Physiological …, 2023 - journals.physiology.org
Augmented vagal signaling may be therapeutic in hypertension. Most studies to date have
used stimulation of the cervical vagal branches. Here, we investigated the effects of chronic …

Sodium homeostasis and hypertension

KK Aung, S Ream-Winnick, M Lane, I Akinlusi… - Current Cardiology …, 2023 - Springer
Abstract Purpose of Review This review aims to summarize and discuss the relationship
between sodium homeostasis and hypertension, including emerging concepts of factors …

8-Aminopurines in the Cardiovascular and Renal Systems and Beyond

EK Jackson, SP Tofovic, Y Chen, LA Birder - Hypertension, 2023 - Am Heart Assoc
Screening of compounds comprising 8-substituted guanine revealed that 8-aminoguanosine
and 8-aminoguanine cause diuresis/natriuresis/glucosuria, yet decrease potassium …

Inflamed adipose tissue: therapeutic targets for obesity-related endothelial injury

W Dai, Z Liu, S Yang, J Kong - Endocrinology, 2023 - academic.oup.com
Cardiovascular disease (CVD) is the leading cause of death worldwide and is primarily
associated with obesity, visceral adiposity, and unhealthy perivascular adipose tissue …

Experimental TET2 Clonal Hematopoiesis Predisposes to Renal Hypertension Through an Inflammasome-Mediated Mechanism

AH Polizio, L Marino, KD Min, Y Yura… - Circulation …, 2024 - ahajournals.org
BACKGROUND: Hypertension incidence increases with age and represents one of the most
prevalent risk factors for cardiovascular disease. Clonal events in the hematopoietic system …

The process of hypertension induced by high-salt diet: Association with interactions between intestinal mucosal microbiota, and chronic low-grade inflammation, end …

T Zheng, Y Wu, K Guo, Z Tan, T Yang - Frontiers in Microbiology, 2023 - frontiersin.org
Inflammation and immunity play a major role in the development of hypertension, and a
potential correlation between host mucosal immunity and inflammatory response regulation …

Benefits of curcumin in the vasculature: A therapeutic candidate for vascular remodeling in arterial hypertension and pulmonary arterial hypertension?

KX Li, ZC Wang, JOA Machuki, MZ Li, YJ Wu… - Frontiers in …, 2022 - frontiersin.org
Growing evidence suggests that hypertension is one of the leading causes of cardiovascular
morbidity and mortality since uncontrolled high blood pressure increases the risk of …