Vincristine-induced peripheral neurotoxicity (VIPN) is a very common side effect of
vincristine chemotherapy among pediatric patients with cancer. Neuropathy may be sensory …

Purpose Vincristine is widely used as anticancer therapy for a variety of hematological
malignancies. The treatment is limited by progressive vincristine-induced neuropathy …

Cytochrome P450 (CYP) enzymes function to catalyze a wide range of reactions, many of
which are critically important for drug response. Members of the human cytochrome P450 3A …

Vincristine (VCR), an effective antitumor drug, has been utilized in several polytherapy
regimens for acute lymphoblastic leukemia, neuroblastoma and rhabdomyosarcoma …

Simple Summary Vincristine is a drug that is part of the treatment for many children with
cancer. Its main side-effect is vincristine-induced peripheral neuropathy (VIPN), which often …

Non-small cell lung cancer is recognized as the deadliest cancer across the globe. In some
areas, it is more common in women than even breast and cervical cancer. Its rise, vaulted by …

Introduction: One of the most common side effects during vincristine (VCR) use is the
establishment of VCR–induced peripheral neuropathy (VIPN). Among several risk factors …

Cancer is the leading cause of death in American children older than 1 year of age. Major
developments in drugs such as thiopurines and optimization in clinical trial protocols for …

This systematic review provides a high-quality synthesis of the empirical evidence regarding
chemotherapy-induced peripheral neuropathy (CIPN) characteristics and patterns described …

长春新碱诱导的周围神经病变的儿童队列研究- PMC Back to Top Skip to main content NIH NLM
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