Optical coherence tomography in neuromyelitis optica spectrum disorders: potential advantages for individualized monitoring of progression and therapy

FC Oertel, H Zimmermann, F Paul, AU Brandt - Epma Journal, 2018 - Springer
Neuromyelitis optica spectrum disorders (NMOSD) are mostly relapsing inflammatory
disorders of the central nervous system (CNS). Optic neuritis (ON) is the first NMOSD-related …

Optical coherence tomography and multiple sclerosis: Update on clinical application and role in clinical trials

J Lambe, S Saidha, RA Bermel - Multiple Sclerosis Journal, 2020 - journals.sagepub.com
Optical coherence tomography (OCT) has emerged as a fast, non-invasive, inexpensive,
high-resolution imaging technique in multiple sclerosis (MS). Retinal layer quantification by …

Multicenter reliability of semiautomatic retinal layer segmentation using OCT

T Oberwahrenbrock, GL Traber, S Lukas… - Neurology …, 2018 - AAN Enterprises
Objective To evaluate the inter-rater reliability of semiautomated segmentation of spectral
domain optical coherence tomography (OCT) macular volume scans. Methods Macular OCT …

Optical coherence tomography in acute optic neuritis: A population‐based study

K Soelberg, S Specovius… - Acta Neurologica …, 2018 - Wiley Online Library
Objectives To measure early structural damage caused by autoimmune inflammatory optic
neuritis (ON) by optical coherence tomography (OCT) in a population‐based cohort …

Retinal damage and visual network reconfiguration defines visual function recovery in optic neuritis

P Villoslada, E Solana, S Alba-Arbalat… - Neurology …, 2024 - neurology.org
Background and Objectives Recovery of vision after acute optic neuritis (AON) is critical to
improving the quality of life of people with demyelinating diseases. The objective of the study …

Acute management of optic neuritis: an evolving paradigm

L Horton, JL Bennett - Journal of Neuro-Ophthalmology, 2018 - journals.lww.com
The current management of acute optic neuritis (ON) is focused on expediting visual
recovery through the use of high-dose intravenous corticosteroids. The recent identification …

Frequent retinal ganglion cell damage after acute optic neuritis

AU Brandt, S Specovius, T Oberwahrenbrock… - Multiple Sclerosis and …, 2018 - Elsevier
Background To identify the extent of ganglion cell damage after first-time optic neuritis (ON)
using the inter-ocular difference between affected and fellow eyes, and whether this …

Predictors of vision impairment in multiple sclerosis

B Sanchez-Dalmau, EH Martinez-Lapiscina… - PLoS …, 2018 - journals.plos.org
Visual impairment significantly alters the quality of life of people with Multiple Sclerosis (MS).
The objective of this study was to identify predictors (independent variables) of visual …

Multiple sclerosis optic neuritis and trans-synaptic pathology on cortical thinning in people with multiple sclerosis

R Ganapathy Subramanian, R Zivadinov… - Journal of …, 2023 - Springer
Background The multi-order visual system represents an excellent testing site regarding the
process of trans-synaptic degeneration. The presence and extent of global versus trans …

Optical coherence tomography as a means to characterize visual pathway involvement in multiple sclerosis

CA Wicki, JVM Hanson… - Current opinion in …, 2018 - journals.lww.com
OCT provides insights into multiple sclerosis beyond the visual pathway. It is capable of
quantifying the major pathological hallmarks of the disease, specifically inflammation and …