[HTML][HTML] Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus

J Isidro, V Borges, M Pinto, D Sobral, JD Santos… - Nature medicine, 2022 - nature.com
The largest monkeypox virus (MPXV) outbreak described so far in non-endemic countries
was identified in May 2022 (refs.,,,,–). In this study, shotgun metagenomics allowed the rapid …

[HTML][HTML] Viral genetic clustering and transmission dynamics of the 2022 mpox outbreak in Portugal

V Borges, MP Duque, JV Martins, P Vasconcelos… - Nature Medicine, 2023 - nature.com
Pathogen genome sequencing during epidemics enhances our ability to identify and
understand suspected clusters and investigate their relationships. Here, we combine …

Mutation rate of SARS-CoV-2 and emergence of mutators during experimental evolution

M Amicone, V Borges, MJ Alves, J Isidro… - … medicine, and public …, 2022 - academic.oup.com
Background and objectives To understand how organisms evolve, it is fundamental to study
how mutations emerge and establish. Here, we estimated the rate of mutation accumulation …

[HTML][HTML] Preliminary results on an autochthonous dengue outbreak in Lombardy Region, Italy, August 2023

I Cassaniti, G Ferrari, S Senatore, E Rossetti… - …, 2023 - eurosurveillance.org
In August 2023, six locally acquired dengue virus 1 infections were detected in Lodi
province, Lombardy Region, in northern Italy, where the vector Aedes albopictus is present …

SARS-CoV-2 whole genome amplification and sequencing for effective population-based surveillance and control of viral transmission

D Harilal, S Ramaswamy, T Loney… - Clinical …, 2020 - academic.oup.com
Background With the gradual reopening of economies and resumption of social life, robust
surveillance mechanisms should be implemented to control the ongoing COVID-19 …

Long-term evolution of SARS-CoV-2 in an immunocompromised patient with non-Hodgkin lymphoma

V Borges, J Isidro, M Cunha, D Cochicho, L Martins… - Msphere, 2021 - Am Soc Microbiol
Recent studies have shown that persistent SARS-CoV-2 infections in immunocompromised
patients can trigger the accumulation of an unusual high number of mutations with potential …

[HTML][HTML] Nosocomial outbreak of SARS-CoV-2 in a “non-COVID-19” hospital ward: virus genome sequencing as a key tool to understand cryptic transmission

V Borges, J Isidro, F Macedo, J Neves, L Silva, M Paiva… - Viruses, 2021 - mdpi.com
Dissemination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in
healthcare institutions affects both patients and health-care workers (HCW), as well as the …

Accelerating bioinformatics implementation in public health

KG Libuit, EL Doughty, JR Otieno… - Microbial …, 2023 - microbiologyresearch.org
We have adopted an open bioinformatics ecosystem to address the challenges of
bioinformatics implementation in public health laboratories (PHLs). Bioinformatics …

[HTML][HTML] Self-sampling monkeypox virus testing in high-risk populations, asymptomatic or with unrecognized Mpox, in Spain

C Agustí, H Martínez-Riveros… - Nature …, 2023 - nature.com
The recent monkeypox virus (MPXV) outbreak was of global concern and has mainly
affected gay, bisexual and other men who have sex with men (GBMSM). Here we assess …

[HTML][HTML] Fulminant echovirus 11 hepatitis in male non-identical twins in northern Italy, April 2023

A Piralla, A Borghesi, A Di Comite, F Giardina… - …, 2023 - eurosurveillance.org
Echovirus 11 (E11) has recently been associated with a series of nine neonatal cases of
severe hepatitis in France. Here, we present severe hepatitis caused by E11 in a pair of …