Virus disinfection mechanisms: the role of virus composition, structure, and function
KR Wigginton, T Kohn - Current opinion in virology, 2012 - Elsevier
Drinking waters are treated for enteric virus via a number of disinfection techniques
including chemical oxidants, irradiation, and heat, however the inactivation mechanisms …
including chemical oxidants, irradiation, and heat, however the inactivation mechanisms …
[HTML][HTML] Trendspotting in the protein data bank
The Protein Data Bank (PDB) was established in 1971 as a repository for the three
dimensional structures of biological macromolecules. Since then, more than 85000 …
dimensional structures of biological macromolecules. Since then, more than 85000 …
De novo protein structure determination from near-atomic-resolution cryo-EM maps
We present a de novo model-building approach that combines predicted backbone
conformations with side-chain fit to density to accurately assign sequence into density maps …
conformations with side-chain fit to density to accurately assign sequence into density maps …
Non-averaged single-molecule tertiary structures reveal RNA self-folding through individual-particle cryo-electron tomography
Large-scale and continuous conformational changes in the RNA self-folding process
present significant challenges for structural studies, often requiring trade-offs between …
present significant challenges for structural studies, often requiring trade-offs between …
Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency
One limitation in electron cryo-microscopy (cryo-EM) is the inability to recover high-
resolution signal from the image-recording media at the full-resolution limit of the …
resolution signal from the image-recording media at the full-resolution limit of the …
A machine learning approach for the identification of protein secondary structure elements from electron cryo‐microscopy density maps
The accuracy of the secondary structure element (SSE) identification from volumetric protein
density maps is critical for de‐novo backbone structure derivation in electron cryo …
density maps is critical for de‐novo backbone structure derivation in electron cryo …
SFG analysis of surface bound proteins: a route towards structure determination
T Weidner, DG Castner - Physical Chemistry Chemical Physics, 2013 - pubs.rsc.org
The surface of a material is rapidly covered with proteins once that material is placed in a
biological environment. The structure and function of these bound proteins play a key role in …
biological environment. The structure and function of these bound proteins play a key role in …
A multi-model approach to assessing local and global cryo-EM map quality
There does not currently exist a standardized indicator of how well cryo-EM-derived models
represent the density from which they were generated. We present a straightforward …
represent the density from which they were generated. We present a straightforward …
[图书][B] Bacteriophages and their structural organisation
E Orlova - 2012 - eprints.bbk.ac.uk
Viruses are extremely small infectious particles that are not visible in a light microscope, and
are able to pass through fine porcelain filters. They exist in a huge variety of forms and infect …
are able to pass through fine porcelain filters. They exist in a huge variety of forms and infect …
Cryo‐electron microscopy modeling by the molecular dynamics flexible fitting method
KY Chan, LG Trabuco, E Schreiner, K Schulten - Biopolymers, 2012 - Wiley Online Library
The increasing power and popularity of cryo‐electron microscopy (cryo‐EM) in structural
biology brought about the development of so‐called hybrid methods, which permit the …
biology brought about the development of so‐called hybrid methods, which permit the …