Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

Streptomycetes are the most abundant source of antibiotics. Typically, each species
produces several antibiotics, with the profile being species specific. Streptomyces coelicolor …

Actinobacteria are Gram-positive bacteria with high G+ C DNA content that constitute one of
the largest bacterial phyla, and they are ubiquitously distributed in both aquatic and …

Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

One of the relevant problems in today's agriculture is related to phytopathogenic
microorganisms that cause between 30–40% of crop losses. Synthetic chemical pesticides …

Covering: up to early 2011 Streptomycetes and other actinobacteria are renowned as a rich
source of natural products of clinical, agricultural and biotechnological value. They are being …

Although the interaction between prokaryotic and eukaryotic microorganisms is crucial for
the functioning of ecosystems, information about the processes driving microbial interactions …

The cyclic dinucleotide c-di-GMP is a signaling molecule with diverse functions in cellular
physiology. Here, we report that c-di-GMP can assemble into a tetramer that mediates the …

Streptomyces coelicolor is the genetically best characterized species of a populous genus
belonging to the gram-positive Actinobacteria. Streptomycetes are filamentous soil …

Actinobacteria is a phylum of gram-positive bacteria with high G+ C content. Among gram-
positive bacteria, actinobacteria exhibit the richest morphological differentiation, which is …