Pseudomonas aeruginosa is an opportunistic pathogen affecting immunocompromised
patients. It is known as the leading cause of morbidity and mortality in cystic fibrosis (CF) …

Biofilms comprising aggregates of microorganisms or multicellular communities have been a
major issue as they cause resistance against antimicrobial agents and biofouling. To date …

Surface sensing is a critical process that promotes the transition to a biofilm lifestyle. Several
surface-sensing mechanisms have been described for a range of species, most involving …

Non-typeable Haemophilus influenzae (NTHi) is an ubiquitous commensal-turned-pathogen
that colonises the respiratory mucosa in airways diseases including Chronic Obstructive …

Pseudomonas aeruginosa has long been established as the most prevalent respiratory
pathogen in Cystic Fibrosis (CF) patients, with opportunistic infection causing profound …

Cystic fibrosis (CF) is a hereditary disease caused by mutations in the gene encoding an
epithelial anion channel. In CF, Cl− and HCO3− hyposecretion, together with mucin …

Background: Organisms trapped in biofilms cause more than 80% of medical infections.
Significant investments are being made to develop methods of removing these biofilms. The …

Bacterial alginates are anionic exopolysaccharides, which are produced by Pseudomonas
and Azotobacter species. Bacterial cells embedded in extracellular polymeric substances …

Pseudomonas aeruginosa, Staphylococcus aureus and Haemophilus influenzae are the
most notorious pathogens associated with pulmonary infections in Cystic Fibrosis (CF) lung …

Hypermutation occurs when the mismatch repair (MMR) system becomes defective due to
eg, mutation. In Pseudomonas aeruginosa (PA), the mutS gene is commonly mutated in …