The geometry at an element centre can generally be predicted based on the number of
electron pairs around it using valence shell electron pair repulsion (VSEPR) theory …

Chemical reactions serve as foundational building blocks for organic chemistry and drug
design. In the era of large AI models, data-driven approaches have emerged to innovate the …

Nonclassical P (III) centers have attracted much attention in recent years. Incorporating a P
(III) center in a rigid bicyclic platform offers a particularly attractive way to invoke significant …

Given the abundance of alcohol feedstocks and the significance of disulfides, we herein
report a nickel-catalyzed direct deoxygenative disulfuration of alcohols with trisulfide …

Organofluorine compounds are vital across multiple sectors, hence highly selective methods
to install fluorine are of considerable importance. The deoxyfluorination of alcohols is a key …

Although extraordinary advances have been achieved by the transition-metal catalysis
system, there is an urgent need to explore and develop alternative methodologies that are …

The selective incorporation of fluoroalkyl motifs into complex organic molecules represents a
significant challenge in fluorine chemistry. Among the various methods allowing the …

Significance: Radosevich and co-workers report an efficient non-basic deoxyfluorination of
alcohols utilizing phosphorus triamide reagent as an alcohol activator, trityl fluoride and a …