Increasing evidence in both experimental and clinical studies suggests that oxidative stress
plays a major role in the pathogenesis of both types of diabetes mellitus. Free radicals are …

For many years, oxidative stress arising from the ubiquitous production of reactive oxygen
species (ROS) has been implicated in the pathogenesis of various eye diseases. While …

Increased oxidative stress and impaired antioxidant defense mechanisms are important
factors in the pathogenesis and progression of diabetes mellitus and other oxidant-related …

Cataract—opacification of the lens—is closely related to diabetes as one of its major late
complications. This review deals with three molecular mechanisms that may be involved in …

Diabetic neuropathy represents a major health problem, as it is responsible for substantial
morbidity, increased mortality, and impaired quality of life. Near-normoglycemia is now …

Oxidative stress is implicated in the pathogenesis of diabetic nephropathy. The attempts to
identify early markers of diabetes-induced renal oxidative injury resulted in contradictory …

The dietary effects of hyperglycemia increasingly result in type 2 diabetes in humans. Two
species, the spiny mice (Acomys cahirinus) and the desert gerbil (Psammomys obesus) …

Alpha lipoic acid (LA) is a cofactor in mitochondrial dehydrogenase complexes. Previous
studies have shown that when administered exogenously LA has antioxidant properties …

Oxidative stress has been discovered to be involved in the progression of diabetes mellitus.
The antioxidant properties of virgin coconut oil (VCO) among other functions might have a …

The effect of alpha-lipoic acid (LA) on the cardiotoxicity induced by doxorubicin (DOX) was
investigated. A single dose of DOX (15mgkg− 1, ip) induced cardiotoxicity manifested …