Imbalances of the oral microbiota and dysbiosis have traditionally been linked to the
occurrence of teeth and oral diseases. However, recent findings indicate that this microbiota …

Post-stroke cognitive impairment (PSCI) is one of the most common complications of stroke,
it is also an important reason for the poor prognosis in stroke patients with motor and speech …

White matter (WM) disease is associated with disruption of the gliovascular unit, which
involves breach of the blood–brain barrier (BBB). We quantified pericytes as components of …

Background The contributions of brain intercellular communication mechanisms, specifically
extracellular vesicles (EV), to the progression of Alzheimer's disease (AD) remain poorly …

Neurovascular unit mural cells called 'pericytes' maintain the blood-brain barrier and local
cerebral blood flow. Pathological changes in the hippocampus predispose to cognitive …

Objective To understand the incidence of stroke in patients with type 2 diabetes mellitus
(T2DM) and/or hypertension (HTN), and provide a basis for the prevention of stroke in these …

We performed a clinicopathological study to assess the burden of small vessel disease
(SVD) type of pathological changes in elderly demented subjects, who had clinical evidence …

Cerebral pericytes are an integral component of the neurovascular unit, which governs the
blood–brain barrier. There is paucity of knowledge on cortical pericytes across different …

Introduction Extracellular vesicles (EVs) have been recognized as key players in numerous
physiological functions. These vesicles alter their compositions attuned to the health and …

Introduction The true global burden of vascular cognitive impairment (VCI) is unknown.
Reducing risk factors for stroke and cardiovascular disease would inevitably curtail VCI …