The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

XY Fu-Shin, PSY Lee, L Yang, N Gao, Y Zhang… - Progress in retinal and …, 2022 - Elsevier
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Epigenetics of Alzheimer's disease

M Nikolac Perkovic, A Videtic Paska, M Konjevod… - Biomolecules, 2021 - mdpi.com
There are currently no validated biomarkers which can be used to accurately diagnose
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …

MicroRNA alteration, application as biomarkers, and therapeutic approaches in neurodegenerative diseases

TPN Nguyen, M Kumar, E Fedele, G Bonanno… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …

The role of microRNAs in solving COVID-19 puzzle from infection to therapeutics: A mini-review

S Paul, LAB Vázquez, PR Reyes-Pérez… - Virus Research, 2022 - Elsevier
Nowadays, one of the major global health concerns is coronavirus disease 2019 (COVID-
19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Applications of nanotechnologies for miRNA-based cancer therapeutics: current advances and future perspectives

LA Bravo-Vázquez, A Méndez-García… - … in Bioengineering and …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are short (18–25 nt), non-coding, widely conserved RNA molecules
responsible for regulating gene expression via sequence-specific post-transcriptional …

Exosome based miRNA delivery strategy for disease treatment

Z Fang, X Zhang, H Huang, J Wu - Chinese Chemical Letters, 2022 - Elsevier
Abstract miRNA, which is a common non-coding RNA, can target various mRNAs to regulate
their physiological activities. Therefore, miRNAs play an important role in various …

Potential effects of mesenchymal stem cell derived extracellular vesicles and exosomal miRNAs in neurological disorders

M Nakano, M Fujimiya - Neural regeneration research, 2021 - journals.lww.com
Mesenchymal stem cells are multipotent cells that possess anti-inflammatory, anti-apoptotic
and immunomodulatory properties. The effects of existing drugs for neurodegenerative …

Gene therapy approach with an emphasis on growth factors: theoretical and clinical outcomes in neurodegenerative diseases

DGT Parambi, KS Alharbi, R Kumar, S Harilal… - Molecular …, 2022 - Springer
The etiology of many neurological diseases affecting the central nervous system (CNS) is
unknown and still needs more effective and specific therapeutic approaches. Gene therapy …

Integration of miRNA's theranostic potential with nanotechnology: promises and challenges for Parkinson's disease therapeutics

KP Tryphena, G Singh, N Jain, P Famta… - Mechanisms of Ageing …, 2023 - Elsevier
Despite the wide research going on in Parkinson's disease (PD), the burden of PD still
remains high and continues to increase. The current drugs available for the treatment of PD …

Dysregulated miRNAs as biomarkers and therapeutical targets in neurodegenerative diseases

G Gentile, G Morello, V La Cognata… - Journal of Personalized …, 2022 - mdpi.com
Alzheimer's disease (AD), Parkinson's disease (PD), and Amyotrophic Lateral Sclerosis
(ALS) are representative neurodegenerative diseases (NDs) characterized by degeneration …